首页> 外文会议>12th Symposium on Bioluminescence and Chemiluminescence, Apr 5-9, 2002, Robinson College, University of Cambridge, UK >ANTIOXIDANT CAPACITY OF VARIOUS SAMPLES MEASURED WITH A CHEMILUMINESCENCE SYSTEM BASED ON GZ-11
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ANTIOXIDANT CAPACITY OF VARIOUS SAMPLES MEASURED WITH A CHEMILUMINESCENCE SYSTEM BASED ON GZ-11

机译:基于GZ-11的化学发光系统测量的各种样品的抗氧化剂容量

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摘要

Free radicals are reactive molecules that attack your cells, tearing through cellular membranes to react and create havoc with nucleic acids, proteins, and enzymes inside. These attacks by free radicals, collectively known as oxidative stress, are capable of causing cells to lose their structure, their function, and eventually destroying them. Sub-optimum dietary intakes of the phenolic antioxidant and vitamin E, are associated with the free radical-mediated destruction of cellular components and thus may promote the pathogenesis of many diseases. There are many other phenolics in the diet such as catechins, flavonols, anthocyanins, coumarins and cinnamic acids which can act as antioxidants in vitro by readily donating hydrogen atoms or electrons from their hydroxyl groups to free radicals, dietary sources include fruit, vegetables, wine and tea. Many antioxidants are marketed with claims that, by blocking the action of free radicals, they can help prevent cardiovascular disease, cancer, and various other conditions with aging. An enhanced chemiluminescence system based on horseradish peroxidase catalyzed peroxidation of GZ-11 was used for the development of an assay for total antioxidant capacity (AC). To explore the possibilities of this system we decided to measure AC of a number of different samples.
机译:自由基是一种攻击性分子,会攻击您的细胞,撕破细胞膜以与内部的核酸,蛋白质和酶发生反应并造成严重破坏。自由基的这些攻击(统称为氧化应激)能够导致细胞丧失其结构,功能并最终破坏它们。膳食中酚类抗氧化剂和维生素E的最佳摄入量与自由基介导的细胞成分破坏有关,因此可能促进许多疾病的发病机理。饮食中还有许多其他酚类,例如儿茶素,黄酮醇,花色苷,香豆素和肉桂酸,它们可以通过将氢原子或羟基的电子容易地提供给自由基而在体外充当抗氧化剂,饮食来源包括水果,蔬菜,葡萄酒和茶。市场上有许多抗氧化剂,声称它们通过阻止自由基的作用,可以帮助预防心血管疾病,癌症以及其他各种衰老情况。基于辣根过氧化物酶催化的GZ-11过氧化的增强化学发光系统用于开发总抗氧化剂能力(AC)的检测方法。为了探索该系统的可能性,我们决定测量许多不同样品的交流电。

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