• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>13th International Symposium on Ceramics in Medicine and the Annual Meeting of the International Society for Ceramics in Medicine 22-26 November 2000 Bologna, Italy >3-D Bone Tissue Engineering with Bioactive, Resorbable Microcarriers
【24h】

3-D Bone Tissue Engineering with Bioactive, Resorbable Microcarriers

机译：具有生物活性，可吸收微载体的3-D骨组织工程

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Novel bioactive, degradable polymer/bioceramic composite microspheres were developed using a solid-in-oil-in-water (s/o/w) emulsion solvent removal method. Modified bioactive glass (MBG) powders were encapsulated into the polylactic acid (PLA) matrix. The microsphere surfaces were transformed into bioactive bone apatite via immersion in simulated physiological fluid (SPF). Osteoblastic cell cultures with the microsphers showed that the cells attached to and formed 3-D aggregates with the microspheres. Extensive extracellular matrix formation and mineralization were observed in the aggregates. Our results support the concept that these new bioactive, degradable composite microspheres may serve as microcarriers for synthesis of bone and other tissues in vitro and in vivo.
机译：新型的生物活性，可降解聚合物/生物陶瓷复合微球是使用水包油中固体（s / o / w）乳液溶剂去除方法开发的。将改性的生物活性玻璃（MBG）粉末封装到聚乳酸（PLA）基质中。通过浸入模拟生理液（SPF）中，微球表面转变为具有生物活性的磷灰石。具有微球的成骨细胞培养表明，细胞附着于微球并与微球形成3-D聚集体。在聚集体中观察到广泛的细胞外基质形成和矿化。我们的结果支持以下概念：这些新的具有生物活性的可降解复合微球可以充当体外和体内合成骨骼和其他组织的微载体。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号