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首页> 外文会议>13th International Symposium on Ceramics in Medicine and the Annual Meeting of the International Society for Ceramics in Medicine 22-26 November 2000 Bologna, Italy >Evaluation of Hydroxyapatite-Putty as a Hemostatic Agent
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Evaluation of Hydroxyapatite-Putty as a Hemostatic Agent

机译：羟基磷灰石腻子作为止血剂的评价

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Although bone wax is often used as a hemostatic agent for bone in surgery, some problems in biocompatibility have been pointed out. Therefore, we have evaluated hydroxyapatite-putty (HAP-putty) as a hemostatic agent for bone. Adhesive strength of HAP-putty to bone increased with the amount of sodium alginate, reaching maximum value in case of containing 8percent sodium alginate. An actual hemostatic ability of HAP-putty was evaluated using rabbits. Bleeding from bone was arrested within 3 minutes. Thus, HAP-putty showed excellent hemostatic ability. Soft tissue response to HAP-putty was evaluated in rabbit subcutaneous tissue. Histological observation revealed slight inflammatory response around HAP-putty. HAP-putty partially transformed to HAP 24 hours after the implantation. In conclusion, HAP-putty could be a useful hemostatic agent for bond due to its good hemostatic ability and excellent biocompatibility.
机译：尽管骨蜡在外科手术中经常用作骨的止血剂，但是已经指出了生物相容性方面的一些问题。因此，我们评估了羟基磷灰石-putty（HAP-putty）作为骨的止血剂。海藻酸钠对牙齿的粘附强度随藻酸钠含量的增加而增加，在含有8％藻酸钠的情况下达到最大值。使用兔子评估了HAP-putty的实际止血能力。在3分钟内停止了从骨头出血。因此，HAP-putty显示出优异的止血能力。在兔皮下组织中评估了软组织对HAP-put的反应。组织学观察发现在HAP周围有轻微的炎症反应。植入后24小时，HAP-putty部分转化为HAP。总之，HAP-putty具有良好的止血能力和出色的生物相容性，因此可能是一种有用的止血剂。

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