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Pre-Treated Bioactive Composite in Rat Soft Tissue

机译:大鼠软组织中的预处理生物活性复合材料

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摘要

Effect of in vitro formed calcium phosphate surface on a bioactive composite was studied in rat subcutaneous tissue. Pre-treatment in simulated body fluid (SBF) for 14 days resulted in the formation of calcium phosphate deposites on the composite surface whereas no formation was observed on the copolymer without bioactive glass. Pre-tretment had no effect on short term soft tissue reactions around the copolymer without bioactive glass rgranules whereas the calcium phosphate surface formed on the composite resulted in delayed healing of the surgical wound. This may be due to mechanical stress caused by rough calcium phosphate surface.
机译:在大鼠皮下组织中研究了体外形成的磷酸钙表面对生物活性复合物的影响。在模拟体液(SBF)中预处理14天导致在复合材料表面形成磷酸钙沉积,而在没有生物活性玻璃的共聚物上未观察到形成。在没有生物活性玻璃微粒的情况下,预脱脂对共聚物周围的短期软组织反应没有影响,而在复合材料上形成的磷酸钙表面则导致手术伤口的愈合延迟。这可能是由于粗糙的磷酸钙表面引起的机械应力。

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