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首页> 外文会议>18th International Symposium on Fine Chemistry and Functional Polymers,4th IUPAC International Symposium on Novel Materials and Their Synthesis(第18届国际精细化学和功能高分子学术讨论会暨第四届IUPAC 国际新型材料及其制备学术讨论会） >Study on pH Sensitivity of a Novel Chitosan Derivative Electrodeposition Film by Electrochemical Method
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Study on pH Sensitivity of a Novel Chitosan Derivative Electrodeposition Film by Electrochemical Method

机译：电化学法研究新型壳聚糖衍生物电沉积膜的pH敏感性

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1.Introduction The stimuli-sensitive system that'responds to the changes of environmental condition such as temperature, pH, chemical species, electrical pulses, etc. Can be effectively applied to many biomedical fields such as drug delivery system and bioseparation process. Therefore, the design of effective stimuli-sensitive system promises the progress in a great many biomedical fields [1]. Chitosan (CS) is a copolymer of D-glucosamine and Nacetylglucosamine derived from naturally abundant chitin, which was reported a potentially useful pharmaceutical material owing to its non-toxicity, high biocompatibility and non-antigenicity that offer advantages for possible clinical uses [2], as a pH-sensitive hydrogel, swells under acidic conditions due to protonation of their free amino groups is currently receiving a great deal of interest for medical and pharmaceutical applications that utilize chitosan in various chemical and physical gel forms [3].
机译：一，简介刺激敏感系统，适应环境条件的变化，例如温度，pH，化学物质，电脉冲等。可有效地应用于许多生物医学领域，如药物输送系统和生物分离过程。因此，有效的刺激敏感系统的设计有望在许多生物医学领域取得进展[1]。壳聚糖（CS）是D-氨基葡萄糖和N乙酰基氨基葡萄糖的共聚物，衍生自自然丰富的几丁质，由于其无毒，高生物相容性和非抗原性，为潜在的临床应用提供了优势，据报道它是一种潜在有用的药物[2]。作为一种对pH敏感的水凝胶，由于其游离氨基的质子化，在酸性条件下会发生溶胀，目前对于利用各种化学和物理凝胶形式的壳聚糖的医学和制药应用引起了广泛的关注[3]。

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