首页> 外文会议>1996 Chinese Peptide Symposium July 21-25, 1996, Chengdu, China >The combination and function of YIGSR and YIGSK
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The combination and function of YIGSR and YIGSK

机译:YIGSR和YIGSK的结合和功能

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摘要

In the studies on metastasis related to laminin receptor YIGSR and YIGSK were identified as playing a critical role in binding of protein laminin to the coresponding receptor. It was found that the terminal amino acid in the laminin pentapeptide produced significant structural changes. In the present paper YIGSR (1) and YIGSK (2) were combined to yield YIGSRYIGSK(3) and YIGSKYIGSR(4) to compare the bioactivity change induced by terminal and centrla amino acid change.
机译:在与层粘连蛋白受体相关的转移研究中,YIGSR和YIGSK被认为在蛋白质层粘连蛋白与相应的受体结合中起关键作用。发现层粘连蛋白五肽中的末端氨基酸产生了显着的结构变化。在本文中,将YIGSR(1)和YIGSK(2)合并生成YIGSRYIGSK(3)和YIGSKYIGSR(4),比较末端和中心氨基酸变化引起的生物活性变化。

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