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The Deep Cerebellar Nuclei: A Comparative. Study between Thin Transverse Sectional Anatomy and Magnetic Resonance Imaging

机译:小脑深核:比较。薄横断面解剖与磁共振成像之间的关系研究

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PURPOSE: The local-ization of the deep cerebellar nuclei is essential in the clinical research of cerebellum. Our research aimed to discriminate the locations of the nuclei on the thin transverse sections and supply anatomic reference for the functional imaging research of cerebellum and stereotactic operations of the correlative motor disorders. MATERIALS AND METHODS: After MRI examination to exclude organic lesions, one head specimen was selected from three cadavers, then embedded with gelatin and frozen under profound hypothermia. Subsequently, the specimen was sliced into 0.1mm transverse sections along AC-PC line with SKC500 computerized freezing milling machine. The sections were photographed and saved in the computer. Finally, the representative sections were observed meticulously, and equivalent in vivo MR images were selected for comparison with the corresponding sections to predict the location and configuration of the cerebellar nuclei. RESULTS: On the sections, the nuclei were four in number on either side, the dentate nucleus appeared as a convoluted band of gray matter on most sections. The fastigial nucleus was situated to the middle line at the anterior end of the superior vermis, and over the roof of Ⅳ ventricle. The emboliform nucleus lay immediately to the medial side of dentate nucleus, and partly covered its hilus. The globose nucleus was an elongated mass, directed anteroposteriorly, and placed medial to emboliform nucleus. CONCLUSION: The locations of the cerebellar nuclei could be discriminated clearly in our data, which could be seen as an anatomic reference for functional imaging research of cerebellum and clinical applications involving with the nuclei.
机译:目的:小脑深核的定位在小脑的临床研究中至关重要。我们的研究旨在区分薄横切面上的核位置,并为相关运动障碍的小脑和立体定向手术的功能成像研究提供解剖学参考。材料与方法:MRI检查排除器质性病变后,从三具尸体中选出一个头部标本,然后包埋明胶并在低温下冷冻。随后,用SKC500电脑冷冻研磨机沿AC-PC线将样品切成0.1mm的横截面。这些部分被拍照并保存在计算机中。最后,仔细观察代表性切片,选择等效的体内MR图像与相应切片进行比较,以预测小脑核的位置和构型。结果:在切片上,每侧的核数为四个,在大多数切片上,齿状核呈灰白色的回旋带状。小脑顶核位于上mis骨前端的中线,在Ⅳ脑室的顶上。栓子状细胞核立即位于齿状细胞核的内侧,部分覆盖了其肺门。球状核为细长块,指向前方,并置于栓子状核的内侧。结论:在我们的数据中可以清楚地区分小脑核的位置,可以作为小脑功能成像研究的解剖学参考以及涉及该核的临床应用。

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  • 来源
  • 会议地点 Qingdao(CN)
  • 作者

    HE Rui-ling; rnWANG Qing-hai;

  • 作者单位

    Lingzhong Fan@Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 250012--Yuchun Tang@Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 250012--Bo Sun@Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 250012--Xiangtao Lin@Shandong Medical Imaging Research Institute, Jinan, 250012--Zhenping Li@Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 250012--Hengtao Qi@Shandong Medical Imaging Research Institute, Jinan, 250012--Shuwei Liu@Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, Jinan 250012--;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng;chi
  • 中图分类 病理解剖学与组织学;
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