The Application of Generalized Linear Model in Interaction Effect Analysis in Clinical Trials of New Drugs of Traditional Chinese Medicine

机译：广义线性模型在中药新药临床试验相互作用效应分析中的应用

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摘要

We apply the generalized linear model to the interactive effect analysis in clinical trials of new drugs of traditional Chinese medicine.We assign a quantitative indicator and a qualitative indicator as the response variable separately.Then we set centers,treatments and baseline as explanatory variables.Thus we establish models containing and not containing the interaction effect of centre and treatment.By the hypothesis testing method,we can deduce whether the interaction effect exists or not.

机译：我们将广义线性模型应用于中药新药临床试验的交互作用分析中，分别将定量指标和定性指标作为反应变量，然后将中心，治疗和基线作为解释变量。我们建立了包含和不包含中心与治疗相互作用效应的模型。通过假设检验的方法，我们可以推断出相互作用效应是否存在。

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来源
《2012 IEEE 5th International conference on management engineering amp; technology of statistics》|2012年|766-769|共4页
会议地点 Qingdao(CN)
作者
Wang Jing; Hu Jingqing;
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作者单位

Clinical Evaluation Center Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing,China;

Clinical Evaluation Center Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing,China;

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会议组织
原文格式 PDF
正文语种 eng
中图分类统计学;
关键词
the generalized linear model; the interactive effect; the traditional Chinese medicine syndrome;

机译：广义线性模型；交互作用；中医证候;

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The Application of Generalized Linear Model in Interaction Effect Analysis in Clinical Trials of New Drugs of Traditional Chinese Medicine

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