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首页> 外文会议>2013 IEEE 1st International Conference on Condition Assessment Techniques in Electrical Systems >Detection of abnormal findings in human RBC in diagnosing G-6-P-D deficiency Haemolytic Anaemia using image processing
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Detection of abnormal findings in human RBC in diagnosing G-6-P-D deficiency Haemolytic Anaemia using image processing

机译：使用图像处理技术检测人RBC异常以诊断G-6-P-D缺乏性溶血性贫血

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摘要

Red Blood Corpuscles are one of the most vital cellular components of human circulatory system. In normal physiological condition, an RBC is circular in front view and biconcave in side view. Also it is 7.5 Itm in diameter and 2 μm in thickness in terms of size. The normal morphology of an RBC undergoes some specific changes due to the consequence of different pathological abnormalities. One of such disease is Haemolytic Anaemia due to Enzymopathy (like G-6-P-D deficiency) where the RBCs take uneven edged ‘Bitten Apple’ like shape. Here in this paper, correct identification of change in normal parameters of red blood cells in an anaemic blood sample has been presented using different image processing tools and techniques. Here the blood smear image is preprocessed by using Weiner filter and Sobel Edge detection method is applied to find the boundary of the corpuscles. Also the region selection is done by which a metric is formulated to determine abnormal shape of the corpuscles. The purpose of this paper is to highlight this medico-technical aspect only.
机译：红血球是人类循环系统最重要的细胞成分之一。在正常的生理条件下，RBC的正视图为圆形，而侧视图为双凹。直径为7.5 Itm，厚度为2μm。由于不同病理异常的结果，红细胞的正常形态会发生一些特定的变化。其中一种疾病是由于酶病引起的溶血性贫血（如G-6-P-D缺乏症），其中红细胞呈不规则的“咬苹果”状。在本文中，使用不同的图像处理工具和技术可以正确识别贫血血液中红细胞正常参数的变化。在这里，使用Weiner滤波器对血液涂片图像进行预处理，并应用Sobel Edge检测方法找到小体的边界。还进行区域选择，通过该区域选择制定度量以确定小体的异常形状。本文的目的仅是强调这一医学技术方面。

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