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Absorption properties of Silver-Silica-Gold Nanomatryushka particle and its optimization for photo-thermal cancer therapy

机译:银-硅-金纳米​​金粉的吸收特性及其对光热癌症治疗的优化

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The tunable optical properties of Silver-Silica-Gold Nanomatryushka particle has been studied theoretically within the Mie scattering framework in context of its application in photo-thermal therapy of cancer. The absorption properties of the particle follow similar physical principles that describes the Gold-Silica-Gold nanomatryushka particles but the lower mode resonance of Silver-Silica-Gold particle has more cross section absorption efficiency. The particles of size 55nm to 70nm would be the best fit for application in the near infrared region of interest. When the core percentage is increased, there is a red shift in the resonance wavelength. Increasing the middle layer on the other hand, first causes a blue shift and later a red shift. A core percentage of 55%-60% and middle layer thickness of 20%-25% would be ideal for photo-thermal therapy. Finally, we discuss the effect of refractive index of the embedding medium on the lower mode energy resonance.
机译:在米氏散射框架内,对银-硅-金-纳米金的粒子的可调光学性质进行了理论研究,并将其应用于癌症的光热疗法中。颗粒的吸收特性遵循描述金-硅-金纳米​​金刚砂颗粒的相似物理原理,但银-硅-金颗粒的较低模式共振具有更大的截面吸收效率。 55nm至70nm的颗粒最适合用于感兴趣的近红外区域。当纤芯百分比增加时,共振波长会发生红移。另一方面,增加中间层会首先导致蓝移,然后导致红移。 55%-60%的核心百分比和20%-25%的中间层厚度对于光热疗法是理想的。最后,我们讨论了嵌入介质的折射率对低模能量共振的影响。

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