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首页> 外文会议>2017 International Conference on Rehabilitation Robotics >Therapeutic effects of anti-gravity treadmill (AlterG) training on reflex hyper-excitability, corticospinal tract activities, and muscle stiffness in children with cerebral palsy
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Therapeutic effects of anti-gravity treadmill (AlterG) training on reflex hyper-excitability, corticospinal tract activities, and muscle stiffness in children with cerebral palsy

机译：反重力跑步机（AlterG）训练对脑瘫患儿反射性过度​​兴奋，皮质脊髓束活动和肌肉僵硬的治疗作用

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摘要

We aimed to study therapeutic effects of antigravity treadmill (AlterG) training on reflex hyper-excitability, muscle stiffness, and corticospinal tract (CST) function in children with spastic hemiplegic cerebral palsy (CP). Three children received AlterG training 3 days per week for 8 weeks as experimental group. Each session lasted 45 minutes. One child as control group received typical occupational therapy for the same amount of time. We evaluated hyper-excitability of lower limb muscles by H-reflex response. We quantified muscle stiffness by sonoelastography images of the affected muscles. We quantified CST activity by transcranial magnetic stimulation (TMS). We performed the evaluations before and after training for both groups. H response latency and maximum M-wave amplitude were improved in experimental group after training compared to control group. Two children of experimental group had TMS response. Major parameters of TMS (i.e. peak-to-peak amplitude of motor evoked potential (MEP), latency of MEP, cortical silent period, and intensity of pulse) improved for both of them. Three parameters of texture analysis of sonoelastography images were improved for experimental group (i.e. contrast, entropy, and shear wave velocity). These findings indicate that AlterG training can improve reflexes, muscle stiffness, and CST activity in children with spastic hemiplegic CP and can be considered as a therapeutic tool to improve neuromuscular abnormalities occurring secondary to CP.
机译：我们旨在研究反重力跑步机（AlterG）训练对痉挛性偏瘫性脑瘫（CP）儿童的反射性超兴奋性，肌肉僵硬和皮质脊髓束（CST）功能的治疗作用。作为实验组，三个孩子每周3天接受AlterG培训，共8周。每节持续45分钟。一名儿童作为对照组接受了相同时间的典型职业治疗。我们通过H-反射反应评估了下肢肌肉的过度兴奋性。我们通过对受影响的肌肉进行超声弹性成像来量化肌肉僵硬。我们通过经颅磁刺激（TMS）量化了CST活性。我们在两组训练前后进行了评估。训练后，与对照组相比，实验组的H反应潜伏期和最大M波振幅均得到改善。实验组的两个孩子有TMS反应。 TMS的主要参数（即运动诱发电位（MEP）的峰峰幅度，MEP的潜伏期，皮质沉默期和脉搏强度）均得到改善。实验组改善了超声弹性成像图像的纹理分析的三个参数（即对比度，熵和剪切波速度）。这些发现表明，AlterG训练可以改善痉挛性偏瘫CP儿童的反射，肌肉僵硬和CST活性，可以被视为改善继发于CP的神经肌肉异常的治疗工具。

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  • 会议地点 London(GB)
  • 作者

    Sh. Parvin; A. Taghiloo; A. Irani; M. Mehdi Mirbagheri;

  • 作者单位

    Department of Biomedical Engineering and Medical Physics, Faculty of Medicine, Tehran University of Medical Sciences and Neural Engineering Research Center, Noorafshar Hospital, Tehran, Iran;

    Department of Radiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran;

    Department of Occupational Therapy, Faculty of Rehabilitation, Shahid Beheshti University of Medical Sciences Health Services, Tehran, Iran;

    Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Neural Engineering Research Center, Noorafshar Hospital, Tehran, Iran;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Muscles; Training; Medical treatment; Biomedical imaging; Electromyography; Entropy; Legged locomotion;

    机译：肌肉;训练;药物治疗;生物医学成像;心电图学;熵;腿运动;

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