Aspiration and MASS Measurement of Microparticles and Unicellular Organisms via Micropipette Resonators

机译：通过微量移液器共振器对微粒和单细胞生物进行抽吸和MASS测量

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This paper reports the first mass measurement of specific microparticles and unicellular organisms on slides or dishes by using micropipette resonators with an open end. Micropipette resonators are fabricated by a customized pipette puller with a galvano mirror that widens the effective heating region thus makes pulled pipettes with a relatively long uniform cross-section. Pulled pipettes cut at a desired position to have an open end are then integrated with a piezo actuator and an optical pickup unit (OPU), originally used in optical data storage drives, for real-time frequency readout. The open-end micropipette resonators are thoroughly characterized with various liquids and particles. Silica microparticles and unicellular organisms, Paramecium Aurelia, sitting on a slide glass are successfully measured. This is the first demonstration of measurement-on-demand with fluidic channel integrated resonators.

机译：本文报道了使用带有开口端的微量移液器对载玻片或培养皿上的特定微粒和单细胞生物进行的首次质量测量。微型移液器谐振器是由带有电流镜的定制移液器拉拔器制造的，该电流镜扩大了有效加热区域，因此使拉出的移液器具有相对较长的均匀横截面。然后，将在所需位置切割成具有开口端的已拉出的移液器与一个压电致动器和一个最初用于光学数据存储驱动器的光学拾取器（OPU）集成在一起，以进行实时频率读出。开放式微量移液器谐振器具有各种液体和颗粒的特征。成功地测量了坐在载玻片上的二氧化硅微粒和单细胞生物，Aurelia草履虫。这是流体通道集成谐振器按需测量的首次演示。

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来源
《2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems amp; Eurosensors XXXIII》|2019年|748-751|共4页
会议地点 Berlin(DE)
作者
Juhee Ko; Donghyuk Lee; Bong Jae Lee; Taewook Kang; Sangkeun Kauh; Jungchul Lee;
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作者单位

Korea Advanced Institute of Science Technology, Daejeon, South Korea;

Samsung Electronics, Suwon, South Korea;

Korea Advanced Institute of Science Technology, Daejeon, South Korea;

Sogang University, Seoul, South Korea;

Seoul National University, Seoul, South Korea;

Korea Advanced Institute of Science Technology, Daejeon, South Korea;

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会议组织
原文格式 PDF
正文语种 eng
中图分类
关键词
Resonators; Resonant frequency; Atmospheric measurements; Liquids; Glass; Particle measurements; Silicon compounds;

机译：谐振器;谐振频率;大气测量;液体;玻璃;颗粒测量;硅化合物;;

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专利

1. Comparison of cell mechanical measurements provided by Atomic Force Microscopy (AFM) and Micropipette Aspiration (MPA) [J] . Daza Rafael, Gonzalez-Bermudez Blanca, Cruces Julia, Journal of the mechanical behavior of biomedical materials . 2019,第期

机译：由原子力显微镜（AFM）和微移液素抽吸（MPA）提供的细胞机械测量的比较
2. Beyond mass measurement for single microparticles via bimodal operation of microchannel resonators [J] . Bong Jae Lee, Jungchul Lee Micro and Nano Systems Letters . 2019,第1期

机译：通过微通道谐振器的双峰运行，对单个微粒进行质量测量
3. Integrated Measurement of the Mass and Surface Charge of Discrete Microparticles Using a Suspended Microchannel Resonator [J] . Philip Dextras, Thomas P. Burg, Scott R. Manalis Analytical chemistry . 2009,第11期

机译：使用悬浮微通道谐振器对离散微粒的质量和表面电荷进行集成测量
4. Aspiration and MASS Measurement of Microparticles and Unicellular Organisms via Micropipette Resonators [C] . Juhee Ko, Donghyuk Lee, Bong Jae Lee, International Conference on Solid-State Sensors, Actuators and Microsystems amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp; Eurosensors . 2019

机译：微粒子谐振器的微粒和单细胞生物的抽吸和质量测量
5. Automated Micropipette Aspiration of Single Cells. [D] . Shojaei-Baghini, Ehsan. 2012

机译：单细胞的自动微量移液器抽吸。
6. Integrated Measurement of the Mass and Surface Charge of Discrete Microparticles Using a Suspended Microchannel Resonator [O] . Philip Dextras, Thomas P. Burg, Scott R. Manalis -1

机译：离散微粒的质量和表面电荷的使用悬浮微通道谐振器的综合测试
7. Micropipette Resonator Enabling Targeted Aspiration and Mass Measurement of Single Particles and Cells [O] . -1

机译：MicroPipette谐振器能够实现单个颗粒和细胞的有针对性的抽吸和质量测量

Aspiration and MASS Measurement of Microparticles and Unicellular Organisms via Micropipette Resonators

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