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首页> 外文会议>3rd international symposium on dairy cow nutrition and milk quality proceedings >Effect of subacute ruminal acidosis on mRNA expressions of hypothalamic appetite regulated factors
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Effect of subacute ruminal acidosis on mRNA expressions of hypothalamic appetite regulated factors

机译：亚急性瘤胃酸中毒对下丘脑食欲调节因子mRNA表达的影响

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摘要

Introduction Feeding high concentrate diets induced subacute ruminal acidosis (SARA).SARA occurs often accompany with food intake depression.But the mechanism of this depression in central brain is lacking.Results of Real-time PCR were that,compared with the control group,mRNA expression of hypothalamic agouti-related protein (AgRP) was significantly decreased (P＜0.05),and neuropeptide Y (NPY) mRNA expression showed a tendency to decrease (P=0.052) in the goats of the SARA group.However,no significant differences of pro-opiomelanocortin (POMC) or melanocortin receptor 4 (MCR4) in hypothalamus were observed between two groups.The depression of food intake of SARA goats was associated with the down-regnlatedmRNA expressions of AgRP and NPY in hypothalamus in our study.
机译：简介高浓度饮食喂养可导致亚急性瘤胃酸中毒（SARA）.SARA经常伴有食物摄取抑制，但缺乏中枢神经抑制的机制。实时PCR的结果是，与对照组相比，mRNA下丘脑刺痛相关蛋白（AgRP）的表达显着下降（P ＜0.05），神经肽Y（NPY）mRNA表达呈下降趋势（P ＝ 0.052），但无明显差异。两组之间在下丘脑中观察到了促鸦胆黑素皮质激素（POMC）或黑皮质素受体4（MCR4）的表达。

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  • 来源
  • 会议地点 Beijing(CN)
  • 作者

    H.Dong; S.Wang; Y.Jia; Y.Ni; Y.Zhang; X.Shen; R.Zhao;

  • 作者单位

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

    Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, NanjingAgricultural University, Najing 210095, China;

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