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An algorithm of multiple sequence alignment based on consensus sequence searched by simulated annealing and star alignment

机译:基于模拟退火和星形比对的共有序列搜索的多序列比对算法

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摘要

Sequence alignment is an important method of sequence analysis in biological informatics, by which the characteristics of a gene family can be conveniently determined through consensus sequence. Finding a consensus sequence prior to multiple sequence alignment makes the sequence alignment easier. Thus, the consensus sequence should be produced by simulated annealing and star alignment algorithms. Furthermore, the star alignment can be used to compare each sequence in the consensus sequence.
机译:序列比对是生物学信息学中重要的序列分析方法,通过该序列可以方便地通过共有序列确定基因家族的特征。在多个序列比对之前找到共有序列使得序列比对更加容易。因此,应通过模拟退火和星形比对算法产生共有序列。此外,星形比对可用于比较共有序列中的每个序列。

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