首页> 外文会议>The 7th Asia Pacific Association for Medical Informatics conference proceedings >DISTRIBUTED MOUSE BRAIN SPATIAL DATABASE: AN ARCHITECTURE FOR BRAIN PHENOTYPE IMAGE MINING
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DISTRIBUTED MOUSE BRAIN SPATIAL DATABASE: AN ARCHITECTURE FOR BRAIN PHENOTYPE IMAGE MINING

机译:分布式鼠标脑空间数据库:一种用于脑表型图像挖掘的架构

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摘要

Bioinformatics techniques provide solutions for large-scale biological gene text data mining, thus accelerating the biomedical science development, while it’s still in its infancy for brain image information utilization. The imaging mining on the brain offer the promise for understanding its topology networks, the function of its complex anatomy, thus exploring previously unexplored avenues in neuroscience. Based on the Web2.0 design idea, this study utilized ArcGIS software to establish the rat brain atlas, and uploaded digitalized rat brain atlas to the spatial database in ArcGIS Server, then published it as web pages which could be visited through web browser in a distributed way. Researchers could register and login in their account to upload and share their experimental mouse brain tissue section images. Furthermore, they could map the positive area of brain to share the phenotype data. The spatial informatics tools in ArcGIS could be further used to analyze the certain phenotype properties with the relevant symptoms to aid neuroscience researcher for their investigations.
机译:生物信息技术为大规模生物基因文本数据挖掘提供了解决方案,从而加速了生物医学科学的发展,尽管它仍处于脑图像信息利用的起步阶段。大脑上的影像挖掘为理解其拓扑网络,其复杂解剖结构的功能提供了希望,从而探索了神经科学中以前尚未探索的途径。本研究基于Web2.0的设计思想,利用ArcGIS软件建立了大鼠脑图集,并将数字化的大鼠脑图集上载到ArcGIS Server的空间数据库中,然后将其发布为可通过Web浏览器访问的网页。分布式方式。研究人员可以注册并登录他们的帐户,以上传和共享他们的实验性小鼠脑组织切片图像。此外,他们可以绘制大脑的阳性区域以共享表型数据。 ArcGIS中的空间信息工具可以进一步用于分析具有相关症状的某些表型属性,以帮助神经科学研究者进行研究。

著录项

  • 来源
  • 会议地点 Beijing(CN)
  • 作者单位

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Anatomy, Histology and Embryology;

    Shanghai Medical College of Fudan University;

    Shanghai 200032 China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

    Department of Anatomy, Histology and Embryology;

    Shanghai Medical College of Fudan University;

    Shanghai 200032 China;

    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医药、卫生;
  • 关键词

    Mouse brain atlas; Spatial database; Web 2.0; Neuroinformatics;

    机译:小鼠脑图谱;空间数据库; Web 2.0;神经信息学;

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