Study on expression of variable beta gene subfamilies of human T-cell antigen receptor before and following vaccination with hbsag

机译：hbsag疫苗接种前后人T细胞抗原受体可变β基因亚家族表达的研究

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HBV belong to Hepadnaviriodaea, it can induce acute and chronic hepatitis through parenteral infection. Some patients can develop primary hepacytic cancer(PHC). Tc can prevent virus infection and remove virus by cellular immunity, and T cells also enhance antibody production in B cells. T-cell receptor (TCR) is an important molecule that recognizes antigen in the form of short peptides bound to a major histocompatibility (MHC) molecule, Functional TCR is generated by gene rearrangement. A large of evidence have shown that Ag-specific T-cell use a restricted set of TCR. Changes in the TCR v beta gene subfamilies after vaccination would be considered to provide preliminary evidence of a mechanism to prevent HBV infection and may be used for specific therapy.

机译：乙肝病毒属于肝炎病毒，可通过肠胃外感染引起急性和慢性肝炎。一些患者可以发展为原发性肝细胞癌（PHC）。 Tc可以预防病毒感染并通过细胞免疫去除病毒，T细胞还可以增强B细胞中的抗体产生。 T细胞受体（TCR）是一种重要分子，可识别与主要组织相容性（MHC）分子结合的短肽形式的抗原，功能性TCR通过基因重排产生。大量证据表明，Ag特异的T细胞使用了一组受限的TCR。接种疫苗后，TCR v beta基因亚家族的变化将被认为是预防HBV感染的机制的初步证据，可用于特定治疗。

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来源
《7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai》|2000年|p.41|共1页
会议地点 Shanghai(CN);Shanghai(CN)
作者
Hinghua Li; Xianzhi Guan; Yanbo Sun;
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原文格式 PDF
正文语种 eng
中图分类 Q9;
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HBsAg Vaccination TCR V beta gene subfamily;

机译：HBsAg疫苗接种TCR V beta基因亚家族;
入库时间 2022-08-26 14:28:50

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1. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. [J] . J M Leiden, D P Dialynas, A D Duby, Molecular and Cellular Biology . 1986,第9期

机译：人T淋巴细胞肿瘤系和正常人T细胞克隆中T细胞抗原受体基因的重排和表达：等位基因排除Tiβ基因表达并优先使用J beta 2基因区段的证据。
2. Correlation between clonotypic T-cell receptor beta chain variable region (TCR-V beta) gene expression and aberrant T-cell antigen expression in cutaneous T-cell lymphoma. [J] . Finn DT, Jaworsky C, Chooback L, Journal of cutaneous pathology . 1996,第4期

机译：皮肤T细胞淋巴瘤中克隆型T细胞受体β链可变区（TCR-Vβ）基因表达与异常T细胞抗原表达之间的相关性。
3. Expression profile and clonality of T-cell receptor beta variable genes in normal human endometrium. [J] . Dokouhaki P, Moghadam R, Akbariasbagh F, AJRI: American Journal of Reproductive Immunology . 2006,第5期

机译：正常人子宫内膜中T细胞受体β可变基因的表达谱和克隆性。
4. Study on expression of variable beta gene subfamilies of human T-cell antigen receptor before and following vaccination with hbsag [C] . Hinghua Li, Xianzhi Guan, Yanbo Sun China-Japan international congress of microbiology . 2000

机译：HBsAg疫苗接种前后人T细胞抗原受体可变β基因亚细胞的表达研究
5. T cell development and gamma/delta T cell antigen receptor: I. Structure and rearrangement of murine T cell antigen receptor delta chain gene. II. Expression of fetal type gamma/delta T cell receptor in adult transgenic mice and its effects on T cell development. [D] . Iwashima, Makio. 1990

机译：T细胞发育和γ/δT细胞抗原受体：I.鼠T细胞抗原受体δ链基因的结构和重排。二。胎儿型γ/δT细胞受体在成年转基因小鼠中的表达及其对T细胞发育的影响。
6. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. [O] . J M Leiden, D P Dialynas, A D Duby, 1986

机译：人T淋巴细胞肿瘤细胞系和正常人T细胞克隆中T细胞抗原受体基因的重排和表达：等位基因排除Ti beta基因表达并优先使用J beta 2基因区段的证据。
7. Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. [O] . Leiden, J M, Dialynas, D P, Duby, A D, 1986

机译：人T淋巴细胞肿瘤系和正常人T细胞克隆中T细胞抗原受体基因的重排和表达：等位基因排除Ti beta基因表达并优先使用J beta 2基因区段的证据。

Study on expression of variable beta gene subfamilies of human T-cell antigen receptor before and following vaccination with hbsag

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