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The Research Progress of Liver Fibrosis

机译：肝纤维化的研究进展

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The accurate diagnosis and staging of hepatic fibrosis is crucial for monitoring the progress of liver disease and curative effect. The current gold standard is liver biopsy, but it can’t be used in population-based screening, monitoring the progression of liver disease or observing the curative effect because of its trauma. Serological diagnosis is based on indicators whose specificity and sensitivity is not high, who can’t reflect the degree of liver fibrosis. Functional MR such as DWI and PWI has certain advantages in distinguishing between cirrhosis of the liver and liver fibrosis to a lesser extent. Ultrasonic imaging is becoming the focus of research as a noninvasive, cheap means of assessing fibrosis. Using the morphological index of ultrasonic standard ultrasonographic and extracting the texture characteristics of ultrasonic images combined with certain classification method have made great development in the accurate staging of hepatic fibrosis.
机译：肝纤维化的准确诊断和分期对于监测肝病的进展和疗效至关重要。当前的金标准是肝活检，但由于创伤而不能用于基于人群的筛查，监测肝病的进展或观察疗效。血清学诊断基于特异性和敏感性不高，无法反映肝纤维化程度的指标。功能性MR（例如DWI和PWI）在较小程度上区分肝硬化和肝纤维化方面具有某些优势。超声成像作为一种评估纤维化的非侵入性廉价方法正成为研究的重点。利用超声标准超声的形态学指标，结合一定的分类方法提取超声图像的纹理特征，在肝纤维化的准确分期中取得了长足的发展。

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