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Biomaterials for Tissue Engineering

机译：组织工程用生物材料

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摘要

Tissue engineering has recently attracted a great deal of attention for its potential in repairing,reconstruction, regenerating or replacing tissue in damaged or diseased organs. A number of tissues and organs have already been investigated using this approach including skin, cartilage, liver, bone, tendon, intestine, pancreas and blood vessel etc. The first commercial application was a bioartificial skin product for burn treatment that was introduced in 1990. In 1994, the total revenues for tissue engineering, bioartificial organs and cell therapies were only about $1.3 million, however, the world market is expected to grow to more than $ 2.7 billion by the year 2000. In tissue engineering, new functional living tissue is fabricated using living cells which are usually associated in one way or another with a matrix or scaffold. The living cells implantation can be associated with the matrix in cell culture before implantation. Here biomaterials play a key role in most tissue engineering approaches to create new tissues or biological substitutes for functional replacement. They are used as supportive scaffolds for cells, as conduits for guiding tissue growth, as barriers between transplanted cells and host tissue. The biomaterials used can be degradable or nondegradable ones for tissue reconstruction or substitution. respectively(cf. Figure 1).
机译：组织工程技术由于其修复，重建，再生或替换受损或患病器官中的组织的潜力，最近引起了广泛的关注。已经使用这种方法研究了许多组织和器官，包括皮肤，软骨，肝脏，骨骼，肌腱，肠，胰腺和血管等。第一种商业应用是用于烧伤治疗的生物人工皮肤产品，该产品于1990年推出。 1994年，组织工程，生物人工器官和细胞疗法的总收入仅为130万美元，然而，到2000年，世界市场预计将增长到27亿美元以上。使用活细胞制造的活细胞，这些活细胞通常以一种或另一种方式与基质或支架相关联。活细胞植入可以在植入之前与细胞培养中的基质结合。在这里，生物材料在大多数组织工程方法中发挥关键作用，以创建新的组织或功能替代的生物替代品。它们用作细胞的支持支架，引导组织生长的导管，移植细胞与宿主组织之间的屏障。用于组织重建或替代的生物材料可以是可降解的或不可降解的。分别（参见图1）。

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  • 来源
    《98 workshop on tissue engineering》|1998年|106-112|共7页
  • 会议地点 Tianjin(CN)
  • 作者

    Kang De Yao; Guo Xiang Cheng; Feng Shen; Yu Ji Yin; Wen Guang Liu; Yuan Lu Cui;

  • 作者单位

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

    Research Institute of Polymeric Materials. Tianjin University, Tianjin 3000 72, P. R. China;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物科学的研究方法与技术;
  • 关键词

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