首页> 外文会议>98 workshop on tissue engineering >BIODEGRADABLE POLYMERS FOR TISSUE ENGINEERING: DEVELOPMENT OF AN INJECTABLE, BIODEGRADABLE IMPLANT FOR CARDIOVASCULAR APPLICATIONS
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BIODEGRADABLE POLYMERS FOR TISSUE ENGINEERING: DEVELOPMENT OF AN INJECTABLE, BIODEGRADABLE IMPLANT FOR CARDIOVASCULAR APPLICATIONS

机译:用于组织工程的生物可降解聚合物:开发用于心血管应用的可注射,可生物降解的植入物

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摘要

A novel block copolymer consisting of poly(propylene fumarate), PPF, and poly(ethylene glycol), PEG, was fabricated and evaluated for use as a cardiovascular stent to prevent reclosure of the vessel lumen following balloon angioplasty. This copolymer has been fabricated in a block configuration with two to three homopolymer units in series through a transesterification reaction between the linear polyester and the terminal hydroxyl functionalities of the PEG. This material has been characterized in terms of structure and composition as well as thermal properties and solubility behavior.
机译:制备了由聚(富马酸丙二酯),PPF和聚(乙二醇),PEG组成的新型嵌段共聚物,并进行了评估,以用作心血管支架,以防止球囊血管成形术后血管腔再次闭合。通过线性聚酯和PEG的末端羟基官能团之间的酯交换反应,已将这种共聚物制成具有两个到三个均聚物单元串联的嵌段结构。该材料的特征在于结构和组成以及热性能和溶解性能。

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