Optimizing the sampling density of a wave-front sensor in adaptive optics systems - application to scanning laser ophthalmoscopy

机译：在自适应光学系统中优化波前传感器的采样密度-在扫描激光检眼镜中的应用

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We present the optimization of an adaptive optics loop for retinal imaging. Generally, the wave-front is over-determined compared to the number of corrector elements. The sampling of the sensor can be reduced while maintaining an efficient correction, leading to higher sensitivity, faster correction and larger dynamic range. An analytical model was developed to characterize the link between number of actuators, number of micro-lenses and correction performance. The optimized correction loop was introduced into a scanning laser ophthalmoscope. In vivo images of foveal photoreceptors were recorded and the obtained image quality is equivalent to the state of the art in retinal AO-imaging.

机译：我们目前为视网膜成像的自适应光学环路的优化。通常，与校正元件的数量相比，波前是超定的。可以在保持有效校正的同时减少传感器的采样，从而实现更高的灵敏度，更快的校正和更大的动态范围。开发了一个分析模型来表征执行器数量，微透镜数量和校正性能之间的联系。将优化的校正环引入扫描激光检眼镜。记录中央凹感光体的体内图像，并且获得的图像质量与视网膜AO成像技术水平相当。

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《Adaptive optics and wavefront control for biological systems III》|2017年|1007318.1-1007318.7|共7页
会议地点 San Francisco(US)
作者
Marie Laslandes; Matthias Salas; Christoph K. Hitzenberger; Michael Pircher;
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作者单位

Medical University of Vienna, Center of Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, A-1090 Vienna, Austria;

Medical University of Vienna, Center of Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, A-1090 Vienna, Austria;

Medical University of Vienna, Center of Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, A-1090 Vienna, Austria;

Medical University of Vienna, Center of Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, A-1090 Vienna, Austria;

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正文语种 eng
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关键词
Adaptive optics; Retinal imaging; Scanning laser ophthalmoscopy; Shack Hartmann wave-front sensor;

机译：自适应光学视网膜成像扫描激光检眼镜； Shack Hartmann波前传感器;

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专利

1. Applications of adaptive optics scanning laser ophthalmoscopy. [J] . Roorda A Optometry and vision science: official publication of the American Academy of Optometry . 2010,第4期

机译：自适应光学扫描激光检眼镜的应用。
2. Variation in rod and cone density from the fovea to the mid-periphery in healthy human retinas using adaptive optics scanning laser ophthalmoscopy [J] . Wells-Gray E. M., Choi S. S., Bries A., Eye . 2016,第8期

机译：使用自适应光学扫描激光检眼镜在健康人视网膜中从中央凹到中周边的视杆和视锥细胞密度变化
3. Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography [J] . M. Pircher, R. J. Zawadzki, J. W. Evans, Optics Letters . 2008,第1期

机译：利用自适应光学增强扫描激光检眼镜和高速横向扫描光学相干断层扫描技术同时成像人锥状马赛克
4. Optimizing the sampling density of a wave-front sensor in adaptive optics systems - application to scanning laser ophthalmoscopy [C] . Marie Laslandes, Matthias Salas, Christoph K. Hitzenberger, Conference on adaptive optics and wavefront control for biological systems III . 2017

机译：优化自适应光学系统中的波前传感器的采样密度 - 扫描激光眼镜镜的应用
5. Development of Swept Source Optical Coherence Tomography and Adaptive Optics Scanning Laser Ophthalmoscopy: Improved Imaging Speed and Handheld Applications [D] . Nankivil, Derek. 2016

机译：扫频光学相干断层扫描和自适应光学扫描激光检眼镜的发展：提高成像速度和手持式应用
6. Applications of Adaptive Optics Scanning Laser Ophthalmoscopy [O] . Austin Roorda -1

机译：自适应光学扫描激光眼镜检查的应用
7. Retinal imaging with a combined adaptive optics/optical coherence tomography and adaptive optics/scanning laser ophthalmoscopy system [O] . Robert J. Zawadzki, Steven M. Jones, Suman Pilli, 2010

机译：具有组合自适应光学/光学相干断层扫描和自适应光学/扫描激光眼科系统的视网膜成像

Optimizing the sampling density of a wave-front sensor in adaptive optics systems - application to scanning laser ophthalmoscopy

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