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首页> 外文会议>Advance in barley sciences : proceedings of 11th international barley genetics symposium >Genome-Wide Association Mapping Identifies Disease Resistance QTLs in Barley Germplasm from Latin America
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Genome-Wide Association Mapping Identifies Disease Resistance QTLs in Barley Germplasm from Latin America

机译：全基因组关联图谱鉴定了拉丁美洲大麦种质的抗病性QTL

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摘要

Diseases are the main problem for barley in Latin America. Spot blotch (caused by Cochliobolus sativus), stripe rust (caused by Puccinia striiformis f.sp. hordei) and leaf rust (caused by Puccinia hordei) are three of the most important diseases that attack the crop in the region. Chemical control of those diseases is both economically and environmentally inappropriate, making the development of durable resistant varieties a priority for breeding programs. However, the availability of new resistance sources is a limiting factor. The objective of this work was to detect genomic regions associated to durable resistance to spot blotch, stripe rust and leaf rust in Latin American germplasm. Associations between disease severities measured in several environments across the Americas and 1536 SNPs (belonging to the Barley OPA1) in a population of 360 genotypes was used to identify genomic regions associated with disease. Several models for association mapping with mixed models were compared. These models considered either the structure of the population (Q) through PCA analysis, the identity by descent through coancestry information (AT), or both. Results show significant marker-trait associations for spot blotch and leaf and stripe rust. Associations are environmentspecific.
机译：疾病是拉丁美洲大麦的主要问题。点斑病（由Cochliobolus sativus引起），条锈病（由Puccinia striiformis f.sp. hordei引起）和叶锈病（由Puccinia hordei引起）是攻击该地区农作物的三种最重要的疾病。对这些疾病的化学控制在经济和环境上都是不合适的，这使得开发抗性持久的品种成为育种计划的重点。但是，新的电阻源的可用性是一个限制因素。这项工作的目的是检测与拉丁美洲种质中对斑点斑，条锈和叶锈的持久抗性相关的基因组区域。在美洲的几种环境中测得的疾病严重程度与360种基因型人群中的1536个SNP（属于Barley OPA1）之间的关联被用于识别与疾病相关的基因组区域。比较了几种用于关联映射的模型与混合模型。这些模型要么通过PCA分析考虑了人口结构（Q），要么通过后裔信息（AT）通过后裔进行了身份识别，要么兼而有之。结果显示斑点斑点和叶和条锈明显的标记-性状关联。关联是特定于环境的。

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