A scalable correlator for multichannel diffuse correlation spectroscopy

机译：用于多通道扩散相关光谱的可扩展相关器

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Diffuse correlation spectroscopy (DCS) is a technique which enables powerful and robust non-invasive optical studies of tissue micro-circulation and vascular blood flow. The technique amounts to autocorrelation analysis of coherent photons after their migration through moving scatterers and subsequent collection by single-mode optical fibers. A primary cost driver of DCS instruments are the commercial hardware-based correlators, limiting the proliferation of multi-channel instruments for validation of perfusion analysis as a clinical diagnostic metric. We present the development of a low-cost scalable correlator enabled by microchip-based time-tagging, and a software-based multi-tau data analysis method. We will discuss the capabilities of the instrument as well as the implementation and validation of 2- and 8-channel systems built for live animal and pre-clinical settings.

机译：扩散相关光谱法（DCS）是一项技术，可以对组织微循环和血管血流进行强大而强大的非侵入性光学研究。该技术相当于对相干光子通过移动散射体进行迁移并随后由单模光纤进行收集后的自相关分析。 DCS仪器的主要成本驱动因素是基于商用硬件的相关器，这限制了用于验证灌注分析作为临床诊断指标的多通道仪器的普及。我们介绍了通过基于微芯片的时间标记实现的低成本可扩展相关器的开发，以及基于软件的多头数据分析方法。我们将讨论该仪器的功能以及为活体动物和临床前环境构建的2通道和8通道系统的实现和验证。

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来源
《Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV》|2016年|969816.1-969816.7|共7页
会议地点 San Francisco CA(US)
作者
Christopher J. Stapels; Noah J. Kolodziejski; Daniel McAdams; Matthew J. Podolsky; Daniel E. Fernandez; Dana Farkas; James F. Christian;
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作者单位

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

Radiation Monitoring Devices, Inc. 44 Hunt St (USA);

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原文格式 PDF
正文语种 eng
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关键词
Diffuse Correlation Spectroscopy; blood perfusion; Hemodynamic monitor;

机译：扩散相关光谱血液灌流血流监测仪;

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4. A scalable correlator for multichannel diffuse correlation spectroscopy [C] . Christopher J. Stapels, Noah J. Kolodziejski, Daniel McAdams, Conference on Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV . 2016

机译：用于多通道漫射相关光谱的可伸缩相关器
5. Early Prediction of Pressure Injury Development Using Diffuse Correlation Spectroscopy [D] . Lafontant, Alec 2019

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6. A scalable correlator for multichannel diffuse correlation spectroscopy [O] . Christopher J. Stapels, Noah J. Kolodziejski, Daniel McAdams, -1

机译：用于多通道扩散相关光谱的可扩展相关器
7. A scalable correlator for multichannel diffuse correlation spectroscopy [O] . Christopher J. Stapels, Noah J. Kolodziejski, Daniel McAdams, 2016

机译：用于多通道漫射相关光谱的可伸缩相关器

A scalable correlator for multichannel diffuse correlation spectroscopy

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