• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Advanced Biomedical and Clinical Diagnostic Systems III; Progress in Biomedical Optics and Imaging; vol.6 no.7 >Surface-enhanced Raman Scattering Molecular nanoprobes
【24h】

Surface-enhanced Raman Scattering Molecular nanoprobes

机译：表面增强拉曼散射分子纳米探针

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nanoparticles are increasingly finding a wide application in the biological studies due to their unique physical and chemical properties. Colloidal nanoparticles are efficient substrate that exhibit surface-enhanced Raman scattering (SERS) phenomenon by enhancing the scattering cross-sections of conjugated Raman active molecules thus enabling highly sensitive biological probes. However, biological and medical applications would require nanoparticles to be conjugated to biomolecules. A universal approach for conjugation of mercarptoacetic acid-capped silver nanoparticles to biomolecules is described. The surface functionalized silver colloids were labeled with a Raman active dye and used for cellular imaging. We also described the use of silver nanoparticle to develop a new class of SERS nanoprobes for molecular recognition and detection of specific nucleic acid sequences.
机译：纳米颗粒由于其独特的物理和化学特性，越来越多地在生物学研究中找到广泛的应用。胶态纳米颗粒是有效的底物，通过增强共轭拉曼活性分子的散射截面，从而表现出表面增强的拉曼散射（SERS）现象，从而实现了高度灵敏的生物探针。但是，生物学和医学应用将需要将纳米颗粒与生物分子结合。描述了一种通用的方法，用于将巯基乙酸封端的银纳米颗粒与生物分子偶联。用拉曼活性染料标记表面官能化的银胶体，并将其用于细胞成像。我们还描述了使用银纳米颗粒来开发一类新的SERS纳米探针，用于分子识别和特定核酸序列的检测。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号