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Optical detection of intravenous infiltration

机译:光学检测静脉浸润

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摘要

Infiltration of medications during infusion therapy results in complications ranging from erythema and pain to tissue necrosis requiring amputation. Infiltration occurs from improper insertion of the cannula, separation of the cannula from the vein, penetration of the vein by the cannula during movement, and response of the vein to the medication. At present, visual inspection by the clinical staff is the primary means for detecting intravenous (Ⅳ) infiltration. An optical sensor was developed to monitor the needle insertion site for signs of Ⅳ infiltration. Initial studies on simulated and induced infiltrations on a swine model validated the feasibility of the methodology. The presence of Ⅳ infiltration was confirmed by visual inspection of the infusion site and/or absence of blood return in the Ⅳ line. Potential sources of error due to illumination changes, motion artifacts, and edema were also investigated. A comparison of the performance of the optical device and blinded expert observers showed that the optical sensor has higher sensitivity and specificity, and shorter detection time than the expert observers. An improved model of the infiltration monitoring device was developed and evaluated in a clinical study on induced infiltrations of healthy adult volunteers. The performance of the device was compared with the observation of a blinded expert observer. The results show that the rates of detection of infiltrations are 98% and 82% for the optical sensor and the observer, respectively. The sensitivity and specificity of the optical sensor are 0.97 and 0.98, respectively.
机译:输液治疗期间药物的渗透会导致并发症,从红斑和疼痛到需要截肢的组织坏死。渗透的发生是由于插管的不正确插入,插管与静脉的分离,运动过程中插管对静脉的渗透以及静脉对药物的反应。目前,临床人员的目视检查是检测静脉(Ⅳ)浸润的主要手段。开发了一种光学传感器来监视针头插入部位是否有Ⅳ浸润迹象。对猪模型的模拟和诱导浸润的初步研究证实了该方法的可行性。通过目视检查输液部位和/或在Ⅳ行中没有回血来确认Ⅳ浸润的存在。还研究了由于照明变化,运动伪影和水肿导致的潜在错误源。光学设备和盲专家观察者的性能比较表明,光学传感器比专家观察者具有更高的灵敏度和特异性,并且检测时间更短。开发了一种改进的渗透监测装置模型,并在对健康成人志愿者的诱导渗透进行的临床研究中进行了评估。将设备的性能与盲目的专业观察者的观察进行了比较。结果表明,对于光学传感器和观察者,渗透的检测率分别为98%和82%。光学传感器的灵敏度和特异性分别为0.97和0.98。

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