首页> 外文会议>Advanced Biomedical and Clinical Diagnostic Systems IV; Progress in Biomedical Optics and Imaging; vol.7 no.3 >Full-field high-speed laser Doppler imaging system for blood-flow measurements
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Full-field high-speed laser Doppler imaging system for blood-flow measurements

机译:全场高速激光多普勒成像系统,用于血流测量

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We describe the design and performance of a new full-field high-speed laser Doppler imaging system developed for mapping and monitoring of blood flow in biological tissue. The total imaging time for 256x256 pixels region of interest is 1.2 seconds. An integrating CMOS image sensor is utilized to detect Doppler signal in a plurality of points simultaneously on the sample illuminated by a divergent laser beam of a uniform intensity profile. The integrating property of the detector improves the signal-to-noise ratio of the measurement, which results in high-quality flow-images provided by the system. The new technique is real-time, non-invasive and the instrument is easy to use. The wide range of applications is one of the major challenges for a future application of the imager. High-resolution high-speed laser Doppler perfusion imaging is a promising optical technique for diagnostic and assessing the treatment effect of the diseases such as e.g. atherosclerosis, psoriasis, diabetes, skin cancer, allergies, peripheral vascular diseases, skin irritancy and wound healing. We present some biological applications of the new imager and discuss the perspectives for the future implementations of the imager for clinical and physiological applications.
机译:我们描述了一种新的全场高速激光多普勒成像系统的设计和性能,该系统用于标测和监视生物组织中的血流。感兴趣的256x256像素区域的总成像时间为1.2秒。利用积分CMOS图像传感器来同时检测由均匀强度分布的发散激光束照射的样品上多个点的多普勒信号。检测器的积分特性改善了测量的信噪比,从而获得了系统提供的高质量流图。新技术是实时的,非侵入性的,并且该仪器易于使用。应用范围广泛是成像仪未来应用的主要挑战之一。高分辨率高速激光多普勒灌注成像是一种有前途的光学技术,用于诊断和评估疾病的治疗效果,例如动脉粥样硬化,牛皮癣,糖尿病,皮肤癌,过敏,周围血管疾病,皮肤刺激和伤口愈合。我们介绍了新成像仪的一些生物学应用,并讨论了该成像仪在临床和生理学应用中未来实现的观点。

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