Developing Polypyrrole-based Oligonucleotide Biosensors

机译：开发基于聚吡咯的寡核苷酸生物传感器

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Many medical, forensic science, environmental and general scientific difficulties may be aided by the existence of suitable biosensors such as gene sensors, body fluid detection DNA sensors, disease detection DNA sensors etc. The sensor technology described here uses the conducting polymer polypyrrole (PPy) as both sensing element and transducer of sensing events. Stability and reproducibility are necessary characteristics of practical biosensors. The stability of polymers can be investigated using electrical impedance spectroscopy (EIS). This work discusses research focused towards creating a stable, reproducible sensor surface for oligonucleotide detection. The effect of electropolymerisation conditions (electropolymerisation method, solvent and electrolyte used), post-growth treatment (cycling and EIS experiments), and the sensing-environment conditions on sensor stability and applicability will be discussed.

机译：存在适当的生物传感器，例如基因传感器，体液检测DNA传感器，疾病检测DNA传感器等，可以帮助解决许多医学，法医学，环境和一般科学难题。此处介绍的传感器技术使用导电聚合物聚吡咯（PPy）作为传感元件和传感事件的传感器。稳定性和可重复性是实际生物传感器的必要特性。可以使用电阻抗光谱（EIS）研究聚合物的稳定性。这项工作讨论了致力于创建稳定，可重现的传感器表面以进行寡核苷酸检测的研究。将讨论电聚合条件（电聚合方法，所用溶剂和电解质），生长后处理（循环和EIS实验）以及传感环境条件对传感器稳定性和适用性的影响。

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《Advanced materials and nanotechnology》|2011年|p.215-218|共4页
会议地点 Wellington(NZ);Wellington(NZ)
作者
Marsilea Adela Booth; SallyAnn Harbison; Jadranka Travas-Sejdic;
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作者单位

Polymer Electronics Research Centre (PERC), University of Auckland, Private Bag 92019, Auckland, New Zealand,Institute of Environmental Science Research Ltd., Private Bag 92-021, Auckland, New Zealand;

Institute of Environmental Science Research Ltd., Private Bag 92-021, Auckland, New Zealand;

Polymer Electronics Research Centre (PERC), University of Auckland, Private Bag 92019, Auckland, New Zealand,MacDiarmid Institute for Advanced Materials and Nanotechnology, New Zealand;

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原文格式 PDF
正文语种 eng
中图分类工程材料一般性问题;
关键词
polypyrrole; DNA sensor; electrical impedance spectroscopy; stability;

机译：聚吡咯DNA传感器电阻抗光谱稳定性;

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1. Developing Polypyrrole-based Oligonucleotide Biosensors [J] . Marsilea Adela Booth, SallyAnn Harbison, Jadranka Travas-Sejdic Materials science forum . 2012,第期

机译：开发基于聚吡咯的寡核苷酸生物传感器
2. Amperometric detection of glucose in fruit juices with polypyrrole-based biosensor with an integrated permselective layer for exclusion of interferences [J] . Ayenimo Joseph G., Adeloju Samuel B. Food Chemistry . 2017,第AUGa15期

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3. Rapid amperometric detection of trace metals by inhibition of an ultrathin polypyrrole-based glucose biosensor [J] . Ayenimo Joseph G., Adeloju Samuel B. Talanta: The International Journal of Pure and Applied Analytical Chemistry . 2016,第Null期

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4. Specific detection of very low concentrations of DNA oligonucleotides with DNA-coated long-period grating biosensor [C] . Karolina H. Czarnecka, Magdalena Dominik, Marta Janczuk-Richter, International conference on optical fiber sensors . 2017

机译：用涂有DNA的长周期光栅生物传感器特异性检测极低浓度的DNA寡核苷酸
5. Surface Templating Using a Photolabile Terpolymer to Construct Mixed Films of Oligomers and Oligonucleotides for DNA Biosensor Development [D] . Lim, Ying 2010

机译：使用光不稳定的三元共聚物进行表面模板化以构建用于DNA生物传感器开发的寡聚体和寡聚核苷酸的混合膜
6. Developing Biosensors in Developing Countries: South Africa as a Case Study [O] . Ronen Fogel, Janice Limson 2016

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7. Wholly printed polypyrrole-based biosensor on flexible substrate [O] . Weng Bo, Shepherd Roderick, Crowley Karl, 2011

机译：基于柔性基材的全印刷聚吡咯基生物传感器

Developing Polypyrrole-based Oligonucleotide Biosensors

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