A Wide Antimicrobial Peptides Search Method Using Fuzzy Modeling

机译：应用模糊建模的广泛的抗菌肽搜索方法

获取原文

获取原文并翻译 | 示例

页面导航

摘要
著录项
相似文献
相关主题

摘要

The search for novel antimicrobial peptides in free databases is a key element to design new antibiotics. Their amino acid physicochemical features impact into the antimicrobial peptides activities. The relationship between the amino acid physicochemical properties and the antimicrobial target might have a fuzzy behavior. This study proposes a sequence similarity and physicochemical search method followed by a fuzzy inference system to find the most appropriated antimicrobial peptides for each domain. The proposed system was tested with NCBI's NR protein data file and the obtained peptide sub dataset will be tested in vitro.

机译：在免费数据库中寻找新的抗菌肽是设计新抗生素的关键要素。它们的氨基酸理化特性影响抗菌肽的活性。氨基酸的理化性质和抗菌目标之间的关系可能具有模糊的行为。这项研究提出了一种序列相似性和理化搜索方法，然后提出了一种模糊推理系统，以找到每个域最合适的抗菌肽。拟议的系统已通过NCBI的NR蛋白数据文件进行了测试，获得的肽亚组数据将在体外进行测试。

著录项

来源
《Advances in bioinformatics and computational biology》|2009年|147-150|共4页
会议地点 Porto Alegre(BR);Porto Alegre(BR)
作者
Fabiano C. Fernandes; William F. Porto; Octavio L. Franco;
展开▼
作者单位

Centro de Analises Proteomicas e Bioquimicas, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, Universidade Catolica de Brasilia, Brasilia - DF, Brazil, 70790-160;

Centro de Analises Proteomicas e Bioquimicas, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, Universidade Catolica de Brasilia, Brasilia - DF, Brazil, 70790-160;

Centro de Analises Proteomicas e Bioquimicas, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, Universidade Catolica de Brasilia, Brasilia - DF, Brazil, 70790-160;

展开▼
会议组织
原文格式 PDF
正文语种 eng
中图分类生物工程学（生物技术）;
关键词
antimicrobial peptides; fuzzy modeling and drug design;

机译：抗菌肽模糊建模与药物设计;

相似文献

外文文献
中文文献
专利

1. Decision tree search methods in fuzzy modeling and classification [J] . L.F. Mendonca, S.M. Vieira, J.M.C. Sousa International Journal of Approximate Reasoning . 2007,第2期

机译：模糊建模与分类中的决策树搜索方法
2. Analogs of the Frog-skin Antimicrobial Peptide Temporin 1Tb Exhibit a Wider Spectrum of Activity and a Stronger Antibiofilm Potential as Compared to the Parental Peptide [J] . Grassi Lucia, Maisetta Giuseppantonio, Maccari Giuseppe, Frontiers in Chemistry . 2017,第2008期

机译：蛙皮抗菌肽Temporin 1Tb的类似物表现出比亲本肽更宽的活性谱和更强的生物膜电位
3. Fuzzy Multicriteria Decision-Making: Models, Methods and Applications Will Appeal To A Wide Audience in Disciplines Where Decision-Making Is Paramount [J] . Energy Business Journal . 2011,第jana3aocta31期

机译：模糊的多准则决策：模型，方法和应用将吸引决策最重要的学科的广泛受众
4. A Wide Antimicrobial Peptides Search Method Using Fuzzy Modeling [C] . Fabiano C. Fernandes, William F. Porto, Octavio L. Franco Brazilian Symposium on Bioinformatics . 2009

机译：一种宽的抗微生物肽搜索方法使用模糊建模
5. A model validation methodology for isolating inconsistent knowledge between fuzzy rule-based and quantitative models using fuzzy simulation [D] . Kim, Gyooseok 1998

机译：一种使用模糊模拟隔离基于规则的模糊模型和定量模型之间的不一致知识的模型验证方法
6. Extracting T–S Fuzzy Models Using the Cuckoo Search Algorithm [O] . Mourad Turki, Anis Sakly 2017

机译：使用布谷鸟搜索算法提取TS模糊模型
7. Analogs of the Frog-skin Antimicrobial Peptide Temporin 1Tb Exhibit a Wider Spectrum of Activity and a Stronger Antibiofilm Potential as Compared to the Parental Peptide [O] . Grassi, Lucia, Maisetta, Giuseppantonio, Maccari, Giuseppe, 2017

机译：蛙皮抗菌肽Temporin 1Tb的类似物表现出比亲本肽更宽的活性谱和更强的生物膜电位

A Wide Antimicrobial Peptides Search Method Using Fuzzy Modeling

摘要

著录项

相似文献

相关主题

期刊订阅