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A neuronal network model with simplified tonotopicity for tinnitus generation and its relief by sound therapy

机译:用于耳鸣产生和通过声音疗法缓解的简化的局部性神经网络模型

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Tinnitus is the perception of sound in the ears or in the head where no external source is present. Sound therapy is one of the most effective techniques for tinnitus treatment that have been proposed. In order to investigate mechanisms of tinnitus generation and the clinical effects of sound therapy, we have proposed conceptual and computational models with plasticity using a neural oscillator or a neuronal network model. In the present paper, we propose a neuronal network model with simplified tonotopicity of the auditory system as more detailed structure. In this model an integrate-and-fire neuron model is employed and homeostatic plasticity is incorporated. The computer simulation results show that the present model can show the generation of oscillation and its cessation by external input. It suggests that the present framework is promising as a modeling for the tinnitus generation and the effects of sound therapy.
机译:耳鸣是在没有外部来源的情况下在耳朵或头部听到声音的感觉。声音疗法是已提出的最有效的耳鸣治疗技术之一。为了研究耳鸣产生的机理和声音疗法的临床效果,我们使用神经振荡器或神经元网络模型提出了具有可塑性的概念和计算模型。在本文中,我们提出了一种神经元网络模型,该模型具有更详细的结构,简化了听觉系统的声音局部性。在该模型中,采用了集成并发射神经元模型,并加入了稳态可塑性。计算机仿真结果表明,该模型可以显示振荡的产生及其通过外部输入的停止。它表明本框架有望作为耳鸣产生和声音治疗效果的模型。

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