首页> 外文会议>Annual Computational Neuroscience Meeting(CNS'02); 20020721-20020725; Chicago,IL; US >Effects of baclofen on the directional selectivity of transient neurons in the catfish retina
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Effects of baclofen on the directional selectivity of transient neurons in the catfish retina

机译:巴氯芬对on鱼视网膜中瞬时神经元方向选择性的影响

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Effects of baclofen on the directional selectivity of the inner retinal neurons were studied using conventional intracellular recording techniques and computer simulations. Baclofen suppressed sustained components, but enhanced transient components of third-order neurons in the catfish retina. In addition, directional selectivity of transient neurons was enhanced by the application of baclofen. The simplified network model was tested to account for the details of directional selectivity observed in the inner retina. Results suggest that the directional selectivity in fish retina could be evoked by the asymmetric distribution of GABAergic third-order neurons.
机译:使用常规细胞内记录技术和计算机模拟研究了巴氯芬对视网膜内神经元定向选择性的影响。巴氯芬抑制suppressed鱼视网膜中的持续成分,但增强了三阶神经元的瞬时成分。此外,巴氯芬的应用增强了瞬时神经元的方向选择性。测试了简化的网络模型以说明内部视网膜中观察到的方向选择性的细节。结果表明,鱼视网膜中的方向选择性可能是由GABA能级三阶神经元的不对称分布引起的。

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