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Using Formal Concept Analysis to Discover Patterns of Non-compliance with Clinical Practice Guidelines: A Case Study in the Management of Breast Cancer

机译:使用形式概念分析发现不符合临床实践准则的模式:乳腺癌治疗中的案例研究

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Clinical decision support systems (CDSSs) may be appropriate tools to promote the use of clinical practice guidelines (CPGs). However, compliance with CPGs is a multifactorial process that relies on the CPGs to be implemented, the physician(s) in charge of the decision, and the patient to manage. Formal concept analysis (FCA) allows to derive implicit relationships from a set of objects described by their attributes, based on the principle of attribute sharing between objects. We used FCA to elicit patient-based formal concepts related to the non-conformity of multidisciplinary staff meetings (MSMs) decisions with CPGs in the domain of breast cancer management. We developed a strategy for selecting attributes and make lattices manageable. We found that when not using the guideline-based CDSS OncoDoc2, patients with bad prognostic factors were associated with non-compliant decisions. This was corrected when the system was used during MSMs.
机译:临床决策支持系统(CDSS)可能是促进临床实践指南(CPG)使用的合适工具。但是,遵守CPG是一个多因素过程,它取决于要实施的CPG,负责决策的医师以及要管理的患者。形式概念分析(FCA)允许根据对象之间属性共享的原理,从一组由其属性描述的对象中派生隐式关系。我们使用FCA来得出与乳腺癌管理领域中CPG的多学科员工会议(MSMs)决策不符合相关的基于患者的正式概念。我们开发了一种选择属性并使晶格易于管理的策略。我们发现,当不使用基于指南的CDSS OncoDoc2时,预后不良的患者会与不依从的决策相关。在MSM中使用系统时,此问题已得到纠正。

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