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首页> 外文会议>Asia-Pacific Bioinformatics Conference(APBC 2003); 200302; Adelaide(AU) >Comparison of Metabolic Pathways using Constraint Graph Drawing
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Comparison of Metabolic Pathways using Constraint Graph Drawing

机译：使用约束图绘制比较代谢途径

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摘要

Databases contain a large amount of data about metabolic pathways, in particular about similar pathways in different species. Biologists are familiar with visual representations of metabolic pathways. Visualizations help them to understand the complex relationships between the components of the pathways, to extract information from the data, and to compare pathways between different species. However, visual interfaces to metabolic pathway databases cannot cope well with the visual comparison of similar pathways in different species. This paper presents a new approach for the visual comparison of metabolic pathways using a constraint graph drawing algorithm. Using layout constraints the same parts of similar pathways in different species are placed side by side, thereby highlighting similarities and differences between these pathways. This visualization method can be used as a visual interface to databases and has been tested with data obtained from the BioPath system and from the KEGG database.
机译：数据库包含有关代谢途径，特别是不同物种中类似途径的大量数据。生物学家熟悉代谢途径的视觉表示。可视化帮助他们了解途径组成部分之间的复杂关系，从数据中提取信息以及比较不同物种之间的途径。然而，代谢途径数据库的视觉界面无法很好地应对不同物种中类似途径的视觉比较。本文提出了一种使用约束图绘制算法对代谢途径进行视觉比较的新方法。使用布局约束，将不同物种中相似途径的相同部分并排放置，从而突出显示这些途径之间的相似点和不同点。这种可视化方法可用作数据库的可视界面，并已通过从BioPath系统和KEGG数据库获得的数据进行了测试。

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