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首页> 外文会议>Asia Pacific Conference on Optics Manufacture; 20070111-13; Hongkong(CN) >Scanning Photoacoustic Tomography in Biological Tissues with a Piezoelectric Double-Ring Sensor
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Scanning Photoacoustic Tomography in Biological Tissues with a Piezoelectric Double-Ring Sensor

机译：用压电双环传感器扫描生物组织中的光声层析成像。

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摘要

Scanning photoacoustic tomography with a piezoelectric double-ring sensor was explored to image biological tissues, and short laser pulses irradiated tissues to generate acoustic waves by thermoelastic expansion. The laser-induced photoacoustic waves were detected by a piezoelectric double-ring sensor. This double-ring sensor has the advantage that it is more sensitive in the forward direction compared with other conventional sensors. An optical fiber for illumination of the sample was integrated with the sensor, which enabled reflection-mode detection of ultrasonic waves. Consequently, two-dimension photoacoustic tomography of biological tissues could be obtained in a manner analogous to the ultrasound B-scan mode by a linear scan over the tissue surfaces. To reach a large depth, 1064nm laser light was used in our experiments. The experimental results showed that the reconstructed photoacoustic images agree well with the structures of the samples. It demonstrated that this sensor has potential to monitoring tumor angiogenesis, and antiangiogenic therapy in vivo.
机译：探索了使用压电双环传感器扫描光声层析成像以对生物组织成像，并用短激光脉冲照射组织以通过热弹性膨胀产生声波。激光感应的光声波由压电双环传感器检测。该双环传感器的优点是，与其他常规传感器相比，它在向前方向上更加敏感。传感器集成了用于照明样品的光纤，从而可以检测超声波的反射模式。因此，可以通过对组织表面进行线性扫描，以类似于超声B扫描模式的方式获得生物组织的二维光声层析成像。为了达到较大的深度，在我们的实验中使用了1064nm激光。实验结果表明，重建的光声图像与样品的结构吻合良好。它表明该传感器具有监测肿瘤血管生成和体内抗血管生成治疗的潜力。

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