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首页> 外文会议>Asian Pacific Conference on Fracture and Strength;APCFS; 20061122-25;20061122-25; Sanya(CN);Sanya(CN) >A Study on Concrescence of Inert Nano Bioceramic Scalpel Wounds
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A Study on Concrescence of Inert Nano Bioceramic Scalpel Wounds

机译：惰性纳米生物陶瓷手术刀创面的研究

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摘要

Over the last 100 years innovative techniques in the fabrication of ceramics have led to their use as high-tech materials. Inert bioceramics, such as ZrO_2, have inherently low level of reactivity compared with other materials such as polymers and metals as well as surface reactive or resorbable ceramics. The aim of this study was to validate the effect of incision using a zirconia inert bioceramic scalpel to incise animal body and to prove incision property of tissues before clinic. The experiments of incisions concrescence using a sterilized Zirconia inert bioceramic scalpel were investigated in this paper. We used 4-month-old inbred line SD rats as experiment animals. They were divided into three groups to undergo incision on the back skin and subcutaneous tissue. The subcutaneous tissue and musculature samples were obtained and analyzed by optical microscopy at 3, 7 and 14 days for histopathological evaluation respectively. The experimental results showed that no wound dehiscence was observed after suture removal at 14 days after the operation. The experiments proved that an inert bioceramic scapel was nontoxic, nonallergenic, and noncarcinogenic for incisions that obtained normal concrescence criteria two weeks after operation.
机译：在过去的100年中，陶瓷制造中的创新技术导致其被用作高科技材料。惰性生物陶瓷（例如ZrO_2）与其他材料（例如聚合物和金属以及表面反应性或可吸收性陶瓷）相比，固有地具有较低的反应性。这项研究的目的是验证使用氧化锆惰性生物陶瓷手术刀切开动物身体的切口的效果，并在临床前证明组织的切开特性。本文研究了使用无菌氧化锆惰性生物陶瓷手术刀进行切口愈合的实验。我们使用4个月大的自交系SD大鼠作为实验动物。将它们分为三组，在背部皮肤和皮下组织上进行切口。获得皮下组织和肌肉组织样品，并分别在第3、7和14天通过光学显微镜分析以进行组织病理学评估。实验结果表明，手术后第14天去除缝合线后未见伤口裂开。实验证明，对于手术后两周达到正常obtained缩标准的切口，惰性生物陶瓷花无毒，无致敏性和非致癌性。

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