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The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells

机译:单线态氧参与亚马逊植物提取物对癌细胞的光化学毒性

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We have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Acai) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen.
机译:自2009年以来,我们一直在寻找基于亚马逊植物提取物的新型光敏剂(PS),用于癌症的光动力治疗(PDT)。在本文中,我们证明了在某些条件下,亚马逊棕榈油桃果实的提取物(流行名称Acai)可用作PST用于小鼠乳腺癌细胞(4T1细胞系)的PDT治疗。我们首先是直接证明植物PS的光动力效应是由于单线态氧。

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