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Silver-Doped Apatite as a Bioactive and an Antimicrobial Bone Material

机译：掺银磷灰石作为生物活性和抗菌性骨材料

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摘要

Phase-pure nanostructured silver-doped hydroxyapatite (nAgHA) of various Ag contents was synthesised. These nAgHA were then evaluated in-vitro using human mesenchymal stem cells (hMSCs) and Escherichia coli (E. coli). Results revealed that hMSCs grew generally well on all nAgHA at all time points. In addition, fewer E. coli were seen attaching on the surface of all nAgHA. Hence, this work demonstrated that nAgHA offers considerable potential as a biomaterial.
机译：合成了各种Ag含量的纯相纳米结构的银掺杂羟基磷灰石（nAgHA）。然后使用人间充质干细胞（hMSCs）和大肠杆菌（E. coli）对这些nAgHA进行体外评估。结果显示，在所有时间点，所有nAgHA上的hMSC普遍生长良好。此外，观察到附着在所有nAgHA表面的大肠杆菌更少。因此，这项工作表明，nAgHA作为生物材料具有巨大的潜力。

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  • 来源
    《Bioceramics 23》|2011年|p.27-30|共4页
  • 会议地点 Istanbul(TR);Istanbul(TR)
  • 作者

    E.S. Thian; P.N. Lim; Z. Shi; B.Y. Tay; K.G. Neoh;

  • 作者单位

    Department of Mechanical Engineering, National University of Singapore, Singapore;

    Department of Mechanical Engineering, National University of Singapore, Singapore;

    Department of Chemical Biomolecular Engineering, National University of Singapore, Singapore;

    Forming Technology Group, Singapore Institute of Manufacturing Technology, Singapore;

    Department of Chemical Biomolecular Engineering, National University of Singapore, Singapore;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物材料学;
  • 关键词

    apatites; E. coli; nanostructured; silver; stem cells;

    机译：磷灰石大肠杆菌;纳米结构银;干细胞;

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