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首页> 外文会议>Biomaterials science: Processing, properties and applications III >MECHANICAL BEHAVIOR IN COMPRESSION AND FLEXURE OF BIOACTIVE GLASS (13- 93) SCAFFOLDS PREPARED BY ROBOTIC DEPOSITION
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MECHANICAL BEHAVIOR IN COMPRESSION AND FLEXURE OF BIOACTIVE GLASS (13- 93) SCAFFOLDS PREPARED BY ROBOTIC DEPOSITION

机译：机器人沉积制备的生物活性玻璃（13-93）支架的压缩和弯曲力学行为

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摘要

There is a need to develop synthetic scaffolds for repairing large defects in load-bearing bones. Our recent work has shown the ability to create strong porous scaffolds of bioactive glass with a grid-like microstructure by robotic deposition (robocasting) which have compressive strengths comparable to cortical bone. In the present work, the mechanical properties of those 13-93 bioactive glass scaffolds were evaluated in compressive and flexural loading to determine their strength, elastic modulus, and Weibull modulus. The scaffolds had a porosity of ～50%, a glass filament diameter of ～300 μm, and a pore width of ～300 urn in the plane of deposition (xy plane) and ～150 urn in z direction. The load in both testing modes was applied in the z direction, and the scaffolds were tested as-fabricated and after immersion in a simulated body fluid (SBF) in vitro. As fabricated, the scaffolds had a strength = 86 ± 9 MPa, elastic modulus =13 + 2 GPa, and Weibull modulus = 12 in compression. The strength, elastic modulus, and Weibull modulus in flexure were 11+3 MPa, 13 + 2 GPa, and 6, respectively. The compressive strength and elastic modulus decreased markedly during the first 2 weeks of immersion in SBF, but more slowly thereafter. The consequences of these results for the potential application of this type of bioactive glass scaffold in the regeneration of loaded bone are discussed.
机译：需要开发用于修复承重骨中大缺陷的合成支架。我们最近的工作表明，可以通过机器人沉积（机器人铸造）来制造具有网格状微结构的坚固多孔生物活性玻璃支架，其抗压强度与皮质骨相当。在目前的工作中，在压缩和弯曲载荷下评估了这些13-93生物活性玻璃支架的机械性能，以确定它们的强度，弹性模量和威布尔模量。支架的孔隙率为〜50％，玻璃丝直径为〜300μm，在沉积平面（xy平面）上的孔径为〜300 um，在z方向上的孔径为〜150 um。两种测试模式下的载荷均沿z方向施加，支架在组装后以及体外浸入模拟体液（SBF）后进行测试。制成后，在压缩状态下，支架的强度为86±9 MPa，弹性模量为13 + 2 GPa，威布尔模量为12。挠曲强度，弹性模量和威布尔模量分别为11 + 3 MPa，13 + 2 GPa和6。在浸入SBF的前2周内，抗压强度和弹性模量显着下降，但随后下降得更慢。讨论了这些结果对于这种类型的生物活性玻璃支架在负载骨骼再生中的潜在应用的后果。

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  • 会议地点 Pittsburgh PA(US)
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    Xin Liu; Mohamed N. Rahaman; Greg E. Hilmas;

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    Department of Materials Science and Engineering Regeneration, Missouri University of Science and Technology, Rolla, Missouri 65409,Center for Bone and Tissue Repair and Regeneration, Missouri University of Science and Technology, Rolla, Missouri 65409;

    Department of Materials Science and Engineering Regeneration, Missouri University of Science and Technology, Rolla, Missouri 65409,Center for Bone and Tissue Repair and Regeneration, Missouri University of Science and Technology, Rolla, Missouri 65409;

    Department of Materials Science and Engineering Regeneration, Missouri University of Science and Technology, Rolla, Missouri 65409;

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