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On alterations in the refractive index and scattering properties of biological tissue caused by histological processing

机译:组织学处理引起的生物组织的折射率和散射特性的变化

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Clinical tissue processing such as formalin fixing, paraffin-embedding and histological staining alters significantly the optical properties of the tissue. We document the alterations in the optical properties of prostate cancer tissue specimens in the 500nm to 700nm spectral range caused by histological processing with quantitative differential interference contrast (qDIC) microscopy. A simple model to explain these alterations is presented at the end.
机译:福尔马林固定,石蜡包埋和组织学染色等临床组织处理会显着改变组织的光学特性。我们记录了由组织学处理与定量差分干涉对比(qDIC)显微镜引起的前列腺癌组织标本在500nm至700nm光谱范围的光学性质的变化。最后提供了一个简单的模型来解释这些更改。

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