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首页> 外文会议>Biomedical Circuits and Systems Conference, 2009. BioCAS 2009 >A low-cost point-of-care system for parallel ELISA essays
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A low-cost point-of-care system for parallel ELISA essays

机译：用于平行ELISA论文的低成本即时医疗系统

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摘要

Chemiluminescence, i.e. the emission of light as a result of a chemical reaction, offers interesting opportunities for developing point-of-care biosensors. However, commercially available systems are expensive and bulky, primarily aimed at laboratory usage. The goal of this work is to present the design and experimental validation of a point-of-care device for proteomics measurements on human serum. The system has been developed for cost-sensitive applications using only Low Cost off-the-shelf components. The system was tested on blood serum, resulting in output signal from spots with specific proteins up-take two order of magnitudes higher than that from control spots: the measured signal was 14mV/s ± 3mV/s on the detection spots, while it was only 260μV/s and 242 μV/s on the control spots.
机译：化学发光，即由于化学反应而发出的光，为开发即时医疗生物传感器提供了有趣的机会。然而，市售系统昂贵且体积大，主要针对实验室用途。这项工作的目的是提出一种用于人体血清蛋白质组学测量的即时检验设备的设计和实验验证。该系统是为仅使用低成本现成组件的成本敏感型应用开发的。该系统在血清上进行了测试，导致具有特定蛋白质的斑点的输出信号比对照斑点的信号吸收高两个数量级：在检测斑点上，测得的信号为14mV / s±3mV / s。在控制点上只有260μV/ s和242μV/ s。

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