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首页> 外文会议>Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on >Application of AIP and MIP CT on Individual GTV Delineation for Tumor Moving with Respiration
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Application of AIP and MIP CT on Individual GTV Delineation for Tumor Moving with Respiration

机译：AIP和MIP CT在个体GTV描绘中的呼吸运动肿瘤应用。

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Objective: To investigate the feasibility of delineating individual gross target volume (GTV) for tumors moving with respiration by using AIP/MIP CT instead of 4D-CT. Methods: CT data of three patients were acquired in Cine mode. The Cine duration time for each couch position is 4~6s, which equals to one breathing cycle plus 1s. The acquired CT data were input to a 4D-CT reconstruction system made in house to reconstruct AIP/MIP and 4D-CT. Then, the characteristics of motion tumor in AIP/MIP and 4D-CT were analyzed. The influences of window width/level on the appearance of periodical motion target in AIP/MIP CT were investigated by using a periodical motion phantom. Results: The GTV in AIP (GTVAIP) and MIP CT (GTVMIP) was bigger than that in extra-inhale phase 4D-CT (GTV4D-in) or extra-exhale phase 4D-CT (GTV4D-ex). The ratios of GTVAIP to GTV4D-in for two patients were 1.30 and 1.07, and the ratios of GTVMIP to GTV4D-ex were 1.57 and 1.21, respectively. AIP/MIP CT with appropriate window width/level can be used to derive the individual target motion envelope. Conclusions: AIP/MIP CT could be used to quickly delineate individual GTV for moving tumor, which may significantly reduce the target delineation laboring. It can be used to replace 4D-CT to derive the individual GTVs for tumors moving with respiratory.
机译：目的：探讨使用AIP / MIP CT代替4D-CT描绘呼吸运动引起的肿瘤的个体总目标体积（GTV）的可行性。方法：以Cine模式采集3例患者的CT数据。每个躺椅位置的电影放映时间为4〜6s，等于一个呼吸周期加1s。将获取的CT数据输入到内部制造的4D-CT重建系统中，以重建AIP / MIP和4D-CT。然后，分析了AIP / MIP和4D-CT中运动性肿瘤的特征。通过使用周期性运动体模，研究了窗口宽度/水平对AIP / MIP CT中周期性运动目标外观的影响。结果：AIP（GTVAIP）和MIP CT（GTVMIP）中的GTV大于呼气外4D-CT（GTV4D-in）或呼气外4D-CT（GTV4D-ex）。两名患者的GTVAIP与GTV4D-in的比率分别为1.30和1.07，GTVMIP与GTV4D-ex的比率分别为1.57和1.21。具有适当的窗口宽度/水平的AIP / MIP CT可用于导出单个目标运动包络线。结论：AIP / MIP CT可用于快速描绘单个GTV转移的肿瘤，可显着减少目标勾画的工作量。它可用于替代4D-CT，以针对呼吸运动的肿瘤推导单个GTV。

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