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首页> 外文会议>Biomedical vibrational spectroscopy VI: Advances in research and industry >A new SERS: scattering enhanced Raman scattering
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A new SERS: scattering enhanced Raman scattering

机译：新的SERS：散射增强的拉曼散射

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摘要

Raman spectroscopy is a powerful technique that can be used to obtain detailed chemical information about a system without the need for chemical markers. It has been widely used for a variety of applications such as cancer diagnosis and material characterization. However, Raman scattering is a highly inefficient process, where only one in 10~(11) scattered photons carry the needed information. Several methods have been developed to enhance this inherently weak effect, including surface enhanced Raman scattering and coherent anti-Stokes Raman scattering. These techniques suffer from drawbacks limiting their commercial use, such as the need for spatial localization of target molecules to a 'hot spot', or the need for complex laser systems. Here, we present a simple instrument to enhance spontaneous Raman scattering using elastic light scattering. Elastic scattering is used to substantially increase the interaction volume. Provided that the scattering medium exhibits very low absorption in the spectral range of interest, a large enhancement factor can be attained in a simple and inexpensive setting. In our experiments, we demonstrate an enhancement of 10~7 in Raman signal intensity. The proposed novel device is equally applicable for analyzing solids, liquids, and gases.
机译：拉曼光谱法是一项强大的技术，可用于获取有关系统的详细化学信息，而无需化学标记。它已被广泛用于各种应用，例如癌症诊断和材料表征。但是，拉曼散射是一种效率很低的过程，其中只有十分之一的散射光子中有一个携带所需的信息。已经开发了几种方法来增强这种固有的弱效应，包括表面增强的拉曼散射和相干的反斯托克斯拉曼散射。这些技术具有限制其商业用途的缺点，例如需要将目标分子空间定位到“热点”，或者需要复杂的激光系统。在这里，我们提出了一种简单的工具，可以利用弹性光散射增强自发拉曼散射。弹性散射用于显着增加相互作用体积。只要散射介质在感兴趣的光谱范围内表现出非常低的吸收率，便可以在简单而廉价的环境中获得较大的增强因子。在我们的实验中，我们证明拉曼信号强度提高了10〜7。所提出的新颖装置同样适用于分析固体，液体和气体。

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