Determining Shapes and Sizes Using TEM Images: Functionalized Nanoparticles

机译：使用TEM图像确定形状和尺寸：功能化的纳米粒子

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摘要

Functionalized nanoparticles to be used for drug delivery must undergo specific verifications in accordance to preestablished requirements. Acquiring TEM (transmission electron microscopy) imaging dealing with nanoparticles functionalization, it is possible to encounter possible faults in the shape of the nanoparticles due to surplus of materials or loss in doses of the materials. Even if the functionalizing instrumentation is equipped with dedicated systems acting accordingly, a further “check and balance” process could be useful using for instance imaging. The paper illustrates the application of an optimized and automatic segmentation technique for determining shapes and sizes the aforementioned nanoparticles.

机译：用于药物递送的功能化纳米颗粒必须根据预先确定的要求进行特定验证。获得处理纳米颗粒功能化的TEM（透射电子显微镜）成像时，由于材料的过量或材料剂量的损失，可能会遇到纳米颗粒形状的缺陷。即使功能化仪器配备了相应的专用系统，使用例如成像技术进行进一步的“检查和平衡”过程也可能很有用。本文说明了一种优化的自动分割技术在确定上述纳米粒子的形状和大小方面的应用。

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来源
《Conference on Nanotechnology for Instrumentation and Measurement》|2016年|5-16|共12页
会议地点 Chemnitz(DE)
作者
A. Lay-Ekuakille; M. Di Paola; F. Conversano; S. Casciaro; P. Sommella; C. Liguori; V. Bhateja;
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作者单位

Dept. of Innovation Engineering University of Salento Lecce 73100 Italy;

National Research Council CNR-IFC Lecce 73100 Italy;

Dept. of In;

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关键词
Nanoparticles; Image segmentation; Image edge detection; Silicon compounds; Shape; Microscopy; Filtering;

机译：纳米颗粒；图像分割图像边缘检测；硅化合物；形状;显微镜；筛选;

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专利

1. Diffusion-Ordered NMR Spectroscopy as a Reliable Alternative to TEM for Determining the Size of Gold Nanoparticles in Organic Solutions [J] . Gabriele Canzi, Anthony A. Mrse, Clifford P. Kubiak The journal of physical chemistry, C. Nanomaterials and interfaces . 2011,第16期

机译：扩散有序NMR光谱法可作为TEM的可靠替代方法，用于确定有机溶液中金纳米颗粒的大小
2. Size Measurement of Nanoparticle Assembly Using Multilevel Segmented TEM Images [J] . PaisarnMuneesawang, ChitnarongSirisathitkul Journal of nanomaterials . 2015,第1期

机译：使用多级分段TEM图像测量纳米颗粒组件的尺寸
3. SIZE OF BOEHMITE NANOPARTICLES BY TEM IMAGES ANALYSIS [J] . Maxime Moreaud, Renaud Revel, Dominique Jeulin, Image analysis and stereology . 2011,第3期

机译：TEM图像分析的勃姆石纳米颗粒尺寸
4. Determining Shapes and Sizes Using TEM Images: Functionalized Nanoparticles [C] . A. Lay-Ekuakille, M. Di Paola, F. Conversano, Nanotechnology for Instrumentation and Measurement . 2016

机译：使用TEM图像确定形状和大小：官能化纳米粒子
5. Synthesis and functionalization of size- and shape-controlled strontium titanate nanoparticles. [D] . Rabuffetti, Federico A. 2010

机译：尺寸和形状受控的钛酸锶纳米颗粒的合成和功能化。
6. Determining the composition of gold nanoparticles: a compilation of shapes sizes and calculations using geometric considerations [O] . Taizo Mori, Torsten Hegmann -1

机译：确定金纳米粒子的组成：形状尺寸和几何考虑的计算的汇编
7. High-Performance Functionalized Magnetic Nanoparticles with Tailored Sizes and Shapes for Localized Hyperthermia Applications [O] . -1

机译：具有定制尺寸和形状的高性能官能化磁性纳米粒子，用于局部热疗应用
8. One-Phase Synthesis of Water-Soluble Gold Nanoparticles with Control over Size and Surface Functionalities [R] . Oh, E., Susumu, K., Goswami, R., 2010

机译：水溶性金纳米粒子的单相合成，控制尺寸和表面功能

Determining Shapes and Sizes Using TEM Images: Functionalized Nanoparticles

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