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Opto-acoustic characterization of chitosan based Gold Nanoparticles (GNPs) synthesized in the presence of monovalent salt

机译:在单价盐存在下合成的壳聚糖基金纳米粒子(GNP)的光声表征

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Several studies, over recent years, focus on the use of chitosan, a biocompatible macromolecule, to form gold nanoparticles (GNPs). In this study, gold nanoparticles were synthesized using chitosan and Chloroauric acid, under stirring which cause microano-gels to form. Ultraviolet (UV) light is used to reduce solution into gold nanoparticles, in which the resulting nanoparticles are biocompatible after this reduction. In effort to obtain nanoparticles of different shape and size using the chitosan, different concentrations of monovalent salt, were added to the chitosan solution. The different signatures of the particles based on the concentration of the salt in the solution are observed using an opto-acoustic setup to detect morphological changes in the particles due to shifts in the absorption resonance. The opto-acoustic measurements are compared to the absorption spectra of the gold nanoparticles. The overall goal of this study is to investigate the influence of chitosan, with the addition of the monovalent salt, on the formation of the biocompatible gold nanoparticles. This characterization will aid in the preparation of measurements to take on these particles in other portions of the electromagnetic spectrum such as radio frequencies.
机译:近年来,几项研究集中于使用壳聚糖(一种生物相容性大分子)形成金纳米颗粒(GNP)。在这项研究中,使用壳聚糖和氯金酸在搅拌下合成了金纳米颗粒,这引起了微/纳米凝胶的形成。紫外线(UV)用于将溶液还原为金纳米颗粒,还原后所得纳米颗粒具有生物相容性。为了使用壳聚糖获得不同形状和尺寸的纳米颗粒,将不同浓度的一价盐加入壳聚糖溶液中。使用光声设置观察基于溶液中盐浓度的颗粒的不同特征,以检测由于吸收共振的移动而导致的颗粒形态变化。将光声测量结果与金纳米颗粒的吸收光谱进行比较。这项研究的总体目标是研究壳聚糖以及单价盐对生物相容性金纳米颗粒形成的影响。这种表征将有助于准备测量以在电磁频谱的其他部分(例如射频)中对这些粒子进行测量。

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