首页> 外文会议>Computational Neuroscience Meeting (CNS'01) Jul, 2001 Monterey, California >Rules relating connections to cortical structure in primate prefrontal cortex
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Rules relating connections to cortical structure in primate prefrontal cortex

机译:灵长类前额叶皮层的皮质结构连接规则

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According to the structural model of prefrontal cortex, the pattern of corticocortical connections is intricately linked to cortical architecture (Cereb. Cortex 7 (1997) 635). We further explored this model by using quantitative methods to describe the structure and connections of prefrontal cortices. Multi-parameter analyses distinguished different cortical types, positioning at one extreme medial and orbitofrontal (limbic) cortices, and at the other extreme, lateral (eulaminate) cortices. The structural model accurately predicted the laminar pattern of connections, and the relative distribution of connections within cortical layers, based on cortical type. This model may provide the foundation to predict the nature of corticocortical processing and its disruption in psychiatric and neurologic diseases, where neuropathology affects specific types of neurons and layers.
机译:根据前额叶皮层的结构模型,皮层皮质连接的模式与皮质结构错综复杂地联系在一起(Cereb。Cortex 7(1997)635)。我们通过定量方法描述前额叶皮层的结构和连接,进一步探索了该模型。多参数分析可区分不同的皮质类型,分别位于一个极端的内侧和眶额(边缘)皮质,以及另一个极端的外侧(消除)皮质。结构模型可根据皮质类型准确预测连接的层状模式以及皮质层内连接的相对分布。该模型可为预测皮层皮层加工的性质及其在精神病和神经病中的破坏提供基础,其中神经病理学会影响特定类型的神经元和层。

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