首页> 外文会议>Computational Neuroscience Meeting (CNS'01) Jul, 2001 Monterey, California >External termination of recurrent bursting in a model of connected local neural sub-networks
【24h】

External termination of recurrent bursting in a model of connected local neural sub-networks

机译:在连接的局部神经网络模型中周期性爆发的外部终止

获取原文
获取原文并翻译 | 示例

摘要

Epileptic seizures are characterized by repetitive synchronous neuronal bursting activity. To study external influences on this activity, a simple model of a chain loop of neuronal networks has been developed with the goal of understanding how external stimuli can contribute to reduction or cessation of such abnormal recurrent bursting activity. Using this simulated loop model, one can demonstrate that an external stimulus that normally can initiate repetitive activity can terminate the bursting activity when applied to a chain loop of sub-networks, which has actively propagating bursts. The ability of external currents to terminate activity is dependent upon loop length and the timing of the applied external stimulus. Termination of propagation in long loops (40-64 sub-networks in this model) requires application of multiple simultaneous stimuli to different sub-networks.
机译:癫痫性发作的特征在于重复的同步神经元爆发活动。为了研究对此活动的外部影响,已经开发了神经网络链环的简单模型,其目的是了解外部刺激如何有助于减少或停止这种异常的反复发作。使用这种模拟的环路模型,可以证明,当正常情况下可以启动重复性活动的外部刺激应用于具有活跃传播突发的子网链环时,可以终止突发活动。外部电流终止活动的能力取决于回路长度和施加的外部刺激的时间。在长回路中终止传播(在此模型中为40-64个子网)需要将多个同时刺激应用于不同的子网。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号