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首页> 外文会议>Computational Neuroscience Meeting (CNS'01) Jul, 2001 Monterey, California >Classes and gradients of prefrontal cortical organization in the primate
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Classes and gradients of prefrontal cortical organization in the primate

机译：灵长类中前额叶皮质组织的类别和梯度

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摘要

Organization and function of the primate prefrontal cortices have been the subject of much discussion and speculation. We quantitatively analyzed the architecture of primate prefrontal cortices in order to provide more reliable foundations for this debate. Stereological data were obtained for more than 20 prefrontal areas in the rhesus monkey, including quantitative information on the densities of neurons, glia and different classes of neurons expressing calcium binding proteins as well as laminar depth. The results of multivariate data analyses indicated that the anatomical organization of prefrontal cortices is determined by categorical factors, such as the existence of a granular layer IV in some areas, and is also shaped by structural gradients, such as a systematic shift of cellular density from deep to superficial cortical layers progressing from medial and orbital to lateral areas.
机译：灵长类前额叶皮层的组织和功能已成为许多讨论和推测的主题。我们定量分析了灵长类前额叶皮层的结构，以便为该辩论提供更可靠的基础。获得了恒河猴20多个前额叶区域的体视学数据，包括有关表达钙结合蛋白的神经元，神经胶质和不同类别的神经元的密度以及层深度的定量信息。多元数据分析的结果表明，前额叶皮层的解剖组织是由分类因素决定的，例如某些区域中存在IV颗粒层，并且还受到结构梯度的影响，例如细胞密度从从内侧和眼眶到外侧区域的深层到浅层皮质层。

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