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Non-invasive biosensor and wireless interrogating system for hypoglycemia

机译:低血糖的无创生物传感器和无线询问系统

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Hypoglycemia― abnormal decrease in blood sugar―is a major obstacle in the management of diabetes and prevention of long-term complications, and it may impose serious effects on the brain, including impairment of memory and other cognitive functions. This paper presents the development of a non-invasive sensor with miniaturized telemetry device in a wrist-watch for monitoring glucose concentration in blood. The sensor concept is based on optical chirality of glucose level in the interstitial fluid. The wrist watch consists of a laser power source of the wavelength compatible with the glucose. A nanofilm with specific chirality is placed at the bottom of the watch. The light then passes through the film and illuminates a small area on the skin. It has been documented that there is certain concentration of sugar level is taken by the intertitial fluid from the blood stream and deposit a portion of it at the dead skin. The wrist-watch when in contact with the outer skin of the human will thus monitor the glucose concentration. A wireless monitoring system in the watch then downloads the data from the watch to a Palm or a laptop computer.
机译:低血糖症(血糖异常降低)是糖尿病管理和预防长期并发症的主要障碍,并且可能对大脑造成严重影响,包括记忆力和其他认知功能受损。本文介绍了一种用于手表中监测血糖浓度的带微型遥测设备的无创传感器的开发。传感器的概念基于组织液中葡萄糖水平的光学手性。手表由波长与葡​​萄糖兼容的激光电源组成。具有特定手性的纳米膜被放置在手表的底部。然后,光线穿过胶片并照亮皮肤上的一小部分区域。已经证明,中间液从血流中获取一定浓度的糖,并将其一部分沉积在死皮上。手表在与人的皮肤接触时将监视葡萄糖浓度。手表中的无线监控系统随后将数据从手表下载到Palm或膝上型计算机。

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