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首页> 外文会议>Conference on Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VIII; 20040126-20040128; San Jose,CA; US >Method of optical self-mixing for pulse wave transit time measurement in comparison with other methods and correlation with blood pressure
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Method of optical self-mixing for pulse wave transit time measurement in comparison with other methods and correlation with blood pressure

机译：与其他方法相比，光学自混合法测量脉搏波传播时间的方法及其与血压的相关性

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This paper is a part of a research to develop convenient method for continuous monitoring of arterial blood pressure by non-invasive and non-oscillometric way. A simple optical method, using self-mixing in a diode laser, which we used for a detection of skin surface vibrations near the artery. These vibrations, which can reveal the pulsate propagation of blood pressure waves along the vasculature, are used for pulse wave registration. The registration of the Pulse Wave Transit Time (PWTT) is based on computing the time delay in different regions of the human body using an ECG as a reference signal. In this study, we compared the method of optical self-mixing with other methods as photoplethysmographic (PPG), bioimpedance (BI) and pulse pressure wave (PW) using piezo-electric transducer for PWTT calculations. In addition, the correlation of PWTT, obtained with different methods, with arterial blood pressure is calculated. In our study, we used a group of volunteers (34 persons) who made the bicycle exercise test. The test consisted of cycling sessions of increasing workloads, during which the HR changed from 60 to 180 beats per minute. In addition, a non-invasive blood pressure (NIBP) was registered with standard sphygmomanometer once per minute during the test and all NIBP measurement values were synchronized to other signals to find exact time moments where the systolic blood pressure was detected (Korotkoff sounds starting point). The computer later interpolated the blood pressure signal in order to get individual value for every heart cycle. Other signals were measured continuously during all tests. At the end of every session, a recovery period was included until person's NIBP and heart rate (HR) normalized. As a result of our study it turned out that time intervals that were calculated from plethysmographic (PPG) waveforms were in the best correlation with systolic blood pressure. The diastolic pressure does not correlate with any of the parameters representing PWTT. The pulse wave signals measured by laser and piezoelectric transducer are very similar and do not have any qualitative differences. Since the detection of pulse wave by piezoelectric transducer is less complicated than laser detection, the piezo transducer should be preferred in such cases, but advantage of optical method of measurement is absent of any mechanical influence to artery.
机译：本文是研究开发一种以无创，无示波方式连续监测动脉血压的便捷方法的研究的一部分。一种简单的光学方法，在二极管激光器中使用自混合，我们将其用于检测动脉附近的皮肤表面振动。这些振动可以揭示出血压波沿脉管系统的脉动传播，被用于脉搏波记录。脉搏波传播时间（PWTT）的注册基于使用ECG作为参考信号计算人体不同区域中的时间延迟。在这项研究中，我们将光学自混合方法与其他方法（如压电容积描记法（PPG），生物阻抗（BI）和脉搏压力波（PW））使用压电换能器进行PWTT计算进行了比较。此外，还计算了用不同方法获得的PWTT与动脉血压的相关性。在我们的研究中，我们使用了一组志愿者（34人）进行了自行车运动测试。该测试包括增加工作量的自行车运动，在此期间，HR从每分钟60拍变为180拍。此外，在测试期间，每分钟向标准血压计记录一次非侵入性血压（NIBP），并将所有NIBP测量值与其他信号同步，以找到检测到收缩压的确切时刻（科罗特科夫听起来是起点）。随后，计算机对血压信号进行插值，以获取每个心动周期的个体值。在所有测试过程中，均连续测量其他信号。每节课结束时，都要包括一个恢复期，直到该人的NIBP和心率（HR）恢复正常为止。我们的研究结果表明，根据体积描记（PPG）波形计算出的时间间隔与收缩压之间的相关性最佳。舒张压与代表PWTT的任何参数都不相关。激光和压电换能器测量的脉搏波信号非常相似，没有任何质量上的差异。由于通过压电换能器检测脉搏波不比激光检测复杂，因此在这种情况下应首选压电换能器，但是光学测量方法的优点是对动脉没有任何机械影响。

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