Combinatorial Models of Gene Assembly

机译：基因组装的组合模型

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We consider formal recombination operations presented in terms of string, graphs and permutations. These operations are faithful to the molecular operations of gene assembly introduced by Prescott, Ehrenfeucht, and Rozenberg . The results mentioned here on the formal operations are mostly stated in the recent book, where one also finds the original references. Ciliates are complex unicellular organisms with a unique nuclear dimorphism: they possess two kinds of nuclei (see reviews by Prescott; Jahn and Klobutcher). The active genome (macronucleus) is formed from an inactive genome (micronucleus). In the process ciliates undergo complex genomic reorganization involving massive parallel DNA elimination, sequence rearrangement, telomere formation, and extensive gene amplification.

机译：我们考虑以字符串，图形和排列形式表示的形式重组操作。这些操作忠实于Prescott，Ehrenfeucht和Rozenberg引入的基因组装的分子操作。在这本书中提到的有关正式操作的结果大部分在最近的书中有所说明，其中也找到了原始的参考文献。纤毛虫是具有独特的核二态性的复杂单细胞生物：它们具有两种核（请参阅Prescott； Jahn和Klobutcher的评论）。活性基因组（巨核）是由非活性基因组（微核）形成的。在此过程中，纤毛虫经历了复杂的基因组重组，包括大量平行DNA消除，序列重排，端粒形成和广泛的基因扩增。

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《Conference on Computability in Europe(CiE 2005); 20050608-12; Amsterdam(NL)》|2005年|P.188-195|共8页
会议地点 Amsterdam(NL)
作者
Tero Harju;
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作者单位

Department of Mathematics, University of Turku, FIN-20014 Turku, Finland;

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原文格式 PDF
正文语种 eng
中图分类计算技术、计算机技术;
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4. Combinatorial Models of Gene Assembly [C] . Tero Harju Conference on Computability in Europe . 2005

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Combinatorial Models of Gene Assembly

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