THE USE OF UP-CONVERTING PHOSPHORS IN BIOLOGICAL DETECTION APPLICATIONS

机译：上转换荧光粉在生物检测应用中的使用

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Up-Converting Phosphor Technology (UPT~(TM)) has been introduced as an alternative to the traditional particle-based in vitro assays. The unique properties of up-converting phosphor reporters offer distinct advantages when used with biologicals. These include a lack of background because no biological matrix up-converts under IR, robust reagents because phosphors are chemically stable in biological matrices and do not photobleach, and multiplexed testing because different colored phosphors can be detected simultaneously using a single infrared source. This presentation will review the theory and properties of up-converting phosphors and their specific applications in rapid tests for cardiac Troponin T in blood and drugs of abuse in saliva.

机译：已经引入了上转换磷光技术（UPT〜TM），以替代传统的基于颗粒的体外测定。与生物制剂一起使用时，上转换荧光报告分子的独特性能具有明显的优势。其中包括缺乏背景，因为没有生物基质可以在红外条件下上转换；有健壮的试剂，因为磷光体在生物基质中化学稳定，不会发生光漂白；以及多重测试，因为可以使用单个红外源同时检测到不同颜色的磷光体。本演讲将回顾上转换荧光粉的理论和特性及其在血液中心脏肌钙蛋白T和唾液滥用药物快速检测中的具体应用。

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来源
《Conference on Fine, Ultrafine and Nano Particles'00, Oct 29 - Nov 1, 2000, Montreal, Quebec, Canada》|2000年|p.73-83|共11页
会议地点 Montreal(CA)
作者
Shang Li;
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STC Technologies, Inc. 150 Webster Street Bethlehem, PA 18015-1389;

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原文格式 PDF
正文语种 eng
中图分类一般工业技术;
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2. 980-nm Laser-Driven Photovoltaic Cells Based on Rare-Earth Up-Converting Phosphors for Biomedical Applications [J] . Zhigang Chen, Lisha Zhang, Yangang Sun, Advanced Functional Materials . 2009,第23期

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3. An up-converting phosphor technology-based lateral flow assay for rapid detection of major mycotoxins in feed: Comparison with enzyme-linked immunosorbent assay and high-performance liquid chromatography-tandem mass spectrometry [J] . Fenghua Zhu, Beibei Zhang, Lianqin Zhu PLoS One . 2021,第4期

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4. Preparation, characterization, and fabrication of uniform coated Y_2O_2S:RE~(3+) up-converting phosphor particles for biological detection applications [C] . Shang Li, Hans Feindt, George Giannaras, Conference on Nanoscale Optics and Applications, Jul 8-9, 2002, Seattle, Washington, USA . 2002

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5. Development platform for immunoassays with up-converting phosphors. [D] . Li, Janice Joyce. 2007

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8. Theory of Particle Count Detection with an Application to the Triggering of Biological Warfare Detection Systems [R] . Yee, E. C. 2000

机译：粒子计数检测理论及其在生物战检测系统触发中的应用

THE USE OF UP-CONVERTING PHOSPHORS IN BIOLOGICAL DETECTION APPLICATIONS

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