首页> 外文会议>Conference on Laser Florence 2001: A Window on the Laser Medicine World, Nov 7-11, 2001, Florence, Italy >Effects of copper vapor laser (CVL) on mice skin: histologic evaluation of damage and tissue stimulation
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Effects of copper vapor laser (CVL) on mice skin: histologic evaluation of damage and tissue stimulation

机译:铜蒸气激光(CVL)对小鼠皮肤的影响:损伤和组织刺激的组织学评估

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This study was to evaluate the effects of the CVL with low energy and short pulse widths. 18 female mice, C57BL/6 (9-11 weeks old) were distributed into four groups. The control group (CG) wasn't exposed to laser beam. Group L1 had 2 laser expositions with 24 hours gap between them (0.5W). Group L2 had 3 expositions (0.5W and 0.25W) and group L3 had 4 expositions (0.25 W). It was used a CVL prototype (510nm, 13 Khz, pulse width of 20 ms and spot size of 0.8cm). 7 days after last laser pulse no groups presented actinic keratosis, tumors or collagen changes. CVL had effective action on pilosebaceous units. High energy with few short pulses induced hair follicles proliferation while low energy with many repetitive short pulses showed increased and specific tissue damage besides hair plugging.
机译:这项研究旨在评估低能量和短脉冲宽度的CVL的影响。将18只雌性小鼠C57BL / 6(9-11周龄)分为四组。对照组(CG)未暴露于激光束。 L1组有2个激光曝光,它们之间有24小时的间隙(0.5W)。 L2组具有3个曝光(0.5W和0.25W),L3组具有4个曝光(0.25 W)。它使用的是CVL原型(510nm,13 Khz,脉冲宽度为20 ms,光斑大小为0.8cm)。最后一次激光脉冲后7天,没有组出现光化性角化病,肿瘤或胶原蛋白变化。 CVL对皮脂腺单位有效。短脉冲很少的高能量诱导毛囊增殖,而短脉冲重复很多的低能量除毛发堵塞外还表现出增加的和特定的组织损伤。

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